Results 161 to 170 of about 311,380 (392)

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

open access: yesEpilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Efficacy and tolerability of perampanel as add‐on therapy in Dravet syndrome: A prospective real‐world study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To investigate the efficacy and tolerability of perampanel (PER) on Dravet syndrome in China by a prospective real‐world study. Methods We prospectively enrolled children with Dravet syndrome from the neurology clinic of Shenzhen Children's Hospital from September 2020 to October 2021.
Han Wang   +9 more
wiley   +1 more source

Resting‐state functional connectivity changes with microburst vagus nerve stimulation therapy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Microburst vagus nerve stimulation (μVNS) may reduce seizure frequency in drug‐resistant epilepsy (DRE) via targeted thalamic plasticity. We prospectively investigated the role of thalamic resting‐state functional connectivity (rsFC) in μVNS effects and hypothesized a relationship between thalamic rsFC and long‐term seizure frequency
Jane B. Allendorfer   +20 more
wiley   +1 more source

The Human Thalamus Is an Integrative Hub for Functional Brain Networks

open access: yesJournal of Neuroscience, 2016
K. Hwang   +3 more
semanticscholar   +1 more source

Regional epilepsy: Unraveling the epileptic phenomenon

open access: yes
Epileptic Disorders, EarlyView.
Shreyashish Roy‐Chowdhury   +5 more
wiley   +1 more source

Late‐onset asystole associated with vagal nerve stimulation

open access: yesEpilepsia Open, EarlyView.
Abstract Vagal nerve stimulation (VNS) is a form of neuromodulation that is an established adjunct in the management of drug‐resistant epilepsy. The common side effects of VNS are cough, dysphonia, or shortness of breath, which are often mild and do not require discontinuation of therapy.
Divya Nagabushana   +3 more
wiley   +1 more source

Chronic thalamic recordings for idiopathic generalized epilepsy and Lennox–Gastaut syndrome: Ictal and interictal electrophysiological findings

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To leverage RNS® System chronic thalamic EEG recordings to compare ictal and interictal thalamic electrophysiology in idiopathic generalized epilepsy (IGE) and Lennox–Gastaut Syndrome (LGS). Methods As part of ongoing clinical trials in IGE and LGS, intracranial EEG data were acquired from the centromedian nucleus (CM) bilaterally ...
Katie L. Bullinger   +3 more
wiley   +1 more source

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