Results 121 to 130 of about 219,391 (317)

Diagnostic Value of Fructosamine and Glycosylated Hemoglobin in Estimating Blood Glucose Level in Diabetic Patients with Thalassemia Major

Medical Laboratory Journal, 2013
Background and Objective: Diabetes mellitus is one of complications that thalassemia major patients face with. Hence, blood glucose monitoring is of vital importance to these patients.
M Kosaryan, MR, A Aliasgharian, M Mousavi, P Roshan   +4 more
doaj  

Thalassemia intermedia in HbH-CS disease with compound heterozygosity for β-thalassemia: challenges in hemoglobin analysis and clinical diagnosis [PDF]

, 2009
Co-inheritance of α-thalassemia with homozygosity or compound heterozygosity for β-thalassemia may ameliorate β-thalassemia major. A wide range of clinical phenotypes is produced depending on the number of α-thalassemia alleles (-α/αα --/αα, --/-α).
George, Elizabeth, Kok, Juan Loong, Tan, Kim Lian, Tan, Mary Anne Jin Ai, Wee, Yong Chui   +4 more
core   +1 more source

Editing aberrant splice sites efficiently restores β-globin expression in β-thalassemia.

Blood, 2019
The thalassemias are compelling targets for therapeutic genome editing in part because monoallelic correction of a subset of hematopoietic stem cells (HSCs) would be sufficient for enduring disease amelioration.
Shuqian Xu, Kevin Luk, Qiuming Yao, Anne H. Shen, Jing Zeng, Yuxuan Wu, Hong‐yuan Luo, C. Brendel, Luca Pinello, D. Chui, S. Wolfe, D. E. Bauer   +11 more
semanticscholar   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

A case of recurrent epilepsy-associated rosette-forming glioneuronal tumor with anaplastic transformation in the absence of therapy. [PDF]

, 2019
Rosette-forming glioneuronal tumor (RGNT) most commonly occurs adjacent to the fourth ventricle and therefore rarely presents with epilepsy. Recent reports describe RGNT occurrence in other anatomical locations with considerable morphologic and genetic ...
Corless, Christopher L, Ferris, Sean P, Grafe, Marjorie, Gultekin, Sakir H, Halfpenny, Aaron, Lawce, Helen, Lucas, Lora, Moore, Stephen, Nazemi, Kellie, Olson, Susan, Perry, Arie, Selden, Nathan, Solomon, David A, Woltjer, Randy, Wood, Matthew D   +14 more
core   +1 more source

Elevated Prevalence of Abnormal Glucose Metabolism and Other Endocrine Disorders in Patients with β-Thalassemia Major: A Meta-Analysis

BioMed Research International, 2019
Background Endocrinopathies are common in patients with β-thalassemia major despite parenteral iron chelation therapy with deferoxamine. Prevalence of abnormal glucose metabolism in previous studies was controversial. The aim of this study was to discuss
Li-Na He, Wei Chen, Yi Yang, Ying-jun Xie, Zeyu Xiong, Diyu Chen, Dian Lu, Nengqing Liu, Yinghong Yang, Xiao-Fang Sun   +9 more
semanticscholar   +1 more source

Comparative efficacy of varicocelectomy and intrauterine insemination in varicocoele patients with mild semen abnormalities: An observational study

Andrology, EarlyView.
Abstract Background Varicocoele is a common cause of male infertility, affecting spermatogenesis through increased testicular temperature, venous stasis, and oxidative stress. Microsurgical subinguinal varicocelectomy improves semen quality, whereas intrauterine insemination is widely used for mild male factor infertility.
Yanlin Ma, Weiming Deng, Tingting Wu, Qi Li, Yuanjie Li, Wenjie Mai, Lizheng Yan, Changwei Liang, Lingxiao Zhang   +8 more
wiley   +1 more source

Thalassemia Major with Idiopathic Hypertriglyceridemia: A Case Report

, 2022
Harsha Bharadwaj Korrapolu, Mahrus A. Rahman, Sai Rashmee Ramavath, Aravya Santosh   +3 more
openalex   +1 more source

Beta-thalassemia: renal complications and mechanisms: a narrative review

Hematology, 2019
Objectives: Beta-thalassemias are a group of recessively autosomal inherited disorders of hemoglobin synthesis, which, due to mutations of the beta-globin gene, lead to various degrees of defective beta-chain production, an imbalance in alpha/beta-globin
C. Demosthenous, E. Vlachaki, C. Apostolou, P. Eleftheriou, A. Kotsiafti, Evangelia Vetsiou, E. Mandala, V. Perifanis, P. Sarafidis   +8 more
semanticscholar   +1 more source

The Ticking Clock: Differential Time‐Dependent Deterioration Between Washed and Thawed Sperm

Andrology, EarlyView.
ABSTRACT Background Cryopreservation is widely used in assisted reproductive technologies. While fresh sperm undergoes gradual time‐dependent deterioration, it remains unclear whether thawed sperm exhibits a more accelerated decline. Objectives To directly compare the rate of deterioration in sperm motility, vitality, and DNA fragmentation between ...
Adiel Kahana, Emily Hamilton, Noga Fuchs Weizman, Sandra E. Kleiman, Shlomit Shabat, Foad Azem, Shimi Barda   +6 more
wiley   +1 more source