Results 21 to 30 of about 102,550 (297)
Deep Maxout Network-based Feature Fusion and Political Tangent Search Optimizer enabled Transfer Learning for Thalassemia Detection [PDF]
arXiv, 2023 Thalassemia is a heritable blood disorder which is the outcome of a genetic defect causing lack of production of hemoglobin polypeptide chains. However, there is less understanding of the precise frequency as well as sharing in these areas. Knowing about the frequency of thalassemia occurrence and dependable mutations is thus a significant step in ...
arxiv
Multiple verification in computational modeling of bone pathologies [PDF]
EPTCS 67, 2011, pp. 82-96, 2011 We introduce a model checking approach to diagnose the emerging of bone pathologies. The implementation of a new model of bone remodeling in PRISM has led to an interesting characterization of osteoporosis as a defective bone remodeling dynamics with respect to other bone pathologies.
arxiv +1 more source
The Prevention of Thalassemia [PDF]
Cold Spring Harbor Perspectives in Medicine, 2013 The thalassemias are among the most common inherited diseases worldwide, affecting individuals originating from the Mediterranean area, Middle East, Transcaucasia, Central Asia, Indian subcontinent, and Southeast Asia. As the diseases require long-term care, prevention of the homozygous state constitutes a major armament in the management. This article
Cao, Antonio, Kan, Yuet Wai
openaire +5 more sources
An overview of complications associated with deferoxamine therapy in thalassemia [PDF]
Journal of Nephropharmacology, 2021 Thalassemic syndromes are the most common genetic diseases in the world that are related to blood transfusion and iron overload in the body. In ß-thalassemia major multiple blood transfusions due to ineffective erythropoiesis lead to iron excess in the ...
Bijan Keikhaei +5 more
doaj +1 more source
A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria [PDF]
, 2004 Parasitized red blood cells (RBCs) from children suffering from severe malaria often adhere to complement receptor 1 (CR1) on uninfected RBCs to form clumps of cells known as "rosettes." Despite a well documented association between rosetting and severe ...
A. O'Donnell +49 more
core +1 more source
Mediterranean Journal of Hematology and Infectious Diseases, 2019 Therapeutic advances, including the availability of oral iron chelators and new non-invasive methods for early detection and treatment of iron overload, have significantly improved the life expectancy and quality of life of patients with thalassemia, with a consequent increase in their reproductive potential and desire to have children.
Raffaella Origa, Federica Comitini
openaire +4 more sources
Hematology Reports, 2019 We propose using a modified amplification refractory mutation system real-time polymerase chain reaction (ARMS RTPCR) technique to exclude the invasive prenatal diagnosis for a non-paternally inherited beta thalassemia mutation in couples atrisk for ...
Narutchala Suwannakhon +6 more
doaj +1 more source
Bromhexine is a potential drug for COVID-19; From hypothesis to clinical trials
Вопросы вирусологии, 2022 COVID-19 (novel coronavirus disease 2019), caused by the SARS-CoV-2 virus, has various clinical manifestations and several pathogenic pathways. Although several therapeutic options have been used to control COVID-19, none of these medications have been ...
S. Bahadoram +6 more
doaj +1 more source
CHMMOTv1 -- Cardiac and Hepatic Multi-Echo (T2*) MRI Images and Clinical Dataset for Iron Overload on Thalassemia Patients [PDF]
arXiv, 2023 Owing to the invasiveness and low accuracy of other tests, including biopsy and ferritin levels, magnetic resonance imaging (T2 and T2*-MRI) has been considered the standard test for patients with thalassemia (THM). Regarding deep learning networks in medical sciences for improving diagnosis and treatment purposes and the existence of minimal resources
arxiv
Scientific Reports, 2022 Ferritin is frequently used to screen some dire consequences of iron overload in β-thalassemia patients. The study aimed to define the best cutoff point of ferritin to screen for cardiac and liver hemosiderosis in these cases.
Hadi Darvishi-Khezri +7 more
doaj +1 more source