Results 1 to 10 of about 5,420,950 (275)
Major Thalassemia, Screening or Treatment: An Economic Evaluation Study in Iran [PDF]
International Journal of Health Policy and Management, 2022 BackgroundBeta-thalassemia minor and thalassemia major are an autosomal recessive disease with hypochromic, microcytic anemia, and morbidities, Today, therapeutic advances have significantly improved the life expectancy of thalassemia major patients, but
Firooz Esmaeilzadeh +4 more
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Endocrine Function in Thalassemia Major [PDF]
The Journal of Clinical Endocrinology & Metabolism, 1968 Abstract Seven patients with thalassemia major, ranging in age from 6½ to 23 yr, were studied. Growth retardation was present in all except the youngest patient. Thyroid and adrenal function was normal. Three patients, however, showed an unexplained increase in the serum protein bound iodine level.
Braden Kuo +2 more
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Hypogonadism in thalassemia major patients
Journal of Clinical & Translational Endocrinology, 2016 Despite recent advances in iron chelation therapy, excess iron deposition in pituitary gonadotropic cells remains one of the major problems in thalassemic patients.
Sasima Srisukh +2 more
doaj +4 more sources
Changes in coagulation status in patients with β-thalassemia in Iraq: A case-control study
Medical Journal of Babylon, 2022 Background: The pathogenesis β-thalassemia is characterized by anemia resulting from reduced β-globin synthesis with low hemoglobin A (HbA) production and higher production of hemoglobin A2 (HbA2) and fetal hemoglobin (HbF).
Hussein Abdalzehra Wadaha +2 more
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Evaluation of the Association of Transferrin Receptor Type 2 Gene Mutation (Y250X) with Iron Overload in Major β-Thalassemia [PDF]
Archives of Razi Institute, 2021 Thalassemia is an inherited blood disorder in which the body produces defective hemoglobin. One of the important processes to reduce the complication of major β-thalassemia is blood transfusion that leads to elevated ferritin levels in the blood.
J Abdulmalek Jaafar, N. A. M Al-Rashedi
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Evaluation of Factors influencing the birth of Thalassemia in Family Members with Thalassemia Major in Southeast Iran in 2021 [PDF]
Journal of Advanced Biomedical Sciences, 2023 Background & Objectives: Beta-thalassemia is one of the complex diseases that causes many social and economic problems for the patient and his family. This study aimed to investigate factors influencing the birth of thalassemia (intermedia or major) in ...
Majid Naderi +5 more
doaj
A Hematologic Disease in the Turkish Republic of Northern Cyprus: Thalassemia Major
Mediterranean Nursing and Midwifery, 2023 Thalassemia is an inherited hematologic disease in which the body makes an abnormal form of hemoglobin. Patients are diagnosed with thalassemia major due to severe anemia and clinical symptoms.
Hazel Şahin Tarım, Fatma Öz
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Molecular Genetics & Genomic Medicine, 2020 Background Hepcidin and hemochromatosis (HFE) are iron regulatory proteins that are encoded by HAMP and HFE genes. Mutation in either HAMP gene or HFE gene causes Hepcidin protein deficiency that can lead to iron overload in beta thalassemia patients ...
Maryam Shah +7 more
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Psychopathology in thalassemia major
Pediatrics International, 2009 AbstractBackground: Thalassemia major (TM) is a chronic disease with adverse emotional effects on both the child and the family. The aim of this study was to investigate the psychiatric state and behavioral problems of children with TM.Methods: Twenty children diagnosed with TM and 34 healthy children were enrolled in this study carried out by the ...
Polat, A. +4 more
openaire +6 more sources
Bezmiâlem Science, 2021 We herein reported the course of Coronavirus diasease-19 (COVID-19) in a 21-year-old patient with thalassemia majo rdisease. The patient who underwent haematopoietic stem cell transplantation in 2013 and developed alloimmunization, presented with high ...
Aziz Ahmad HAMİDİ +2 more
doaj +1 more source