Results 21 to 30 of about 5,420,950 (275)

Pathogenesis of Thalassemia Major-associated Osteoporosis: A Review with Insights from Clinical Experience

Journal of Clinical Research in Pediatric Endocrinology, 2019
Due to increasing life expectancy in thalassemia major (TM), osteoporosis is emerging as a significant problem. Its aetiology is multifactorial, culminating in increased bone resorption and impaired remodelling.
A. Gaudio, N. Morabito, A. Catalano, R. Rapisarda, A. Xourafa, A. Lasco   +5 more
semanticscholar   +1 more source

Overview of the current issues and advances in haemopoietic stem cell transplantation for β-thalassemia major

Thalassemia Reports, 2011
Bone marrow transplantation (BMT) is the only possible curative treatment for β-thalassemia major. The largest experience occurred in Pesaro, Italy, where the BMT was applied after a standard risk assessment.
S.S. Anak
doaj   +1 more source

Relationship between Ferritin Levels with Calcium Levels in Patients Thalassemia β Major in Hospital in Jember

Journal of Agromedicine and Medical Sciences (AMS), 2023
Thalassemia β major is a hereditary disorder caused by mutations in the β-globin gene, which regulates the formation of one of the components that make up hemoglobin. This disorder results in the production of β-globin chains being reduced or not formed.
Fantya Cerebella Aslamy, Rini Riyanti, Cholis Abrori   +2 more
doaj   +1 more source

Elevated Prevalence of Abnormal Glucose Metabolism and Other Endocrine Disorders in Patients with β-Thalassemia Major: A Meta-Analysis

BioMed Research International, 2019
Background Endocrinopathies are common in patients with β-thalassemia major despite parenteral iron chelation therapy with deferoxamine. Prevalence of abnormal glucose metabolism in previous studies was controversial. The aim of this study was to discuss
Li-Na He, Wei Chen, Yi Yang, Ying-jun Xie, Zeyu Xiong, Diyu Chen, Dian Lu, Nengqing Liu, Yinghong Yang, Xiao-Fang Sun   +9 more
semanticscholar   +1 more source

Related and unrelated donor transplantation for β-thalassemia major: results of an international survey.

Blood Advances, 2019
We studied 1110 patients with β-thalassemia major aged ≤25 years who received transplants with grafts from HLA-matched related (n = 677; 61%), HLA-mismatched related (n = 78; 7%), HLA-matched unrelated (n = 252; 23%), and HLA-mismatched unrelated (n ...
Chunfu Li, V. Mathews, Soyoung Kim, B. George, K. Hebert, Hua Jiang, Changgang Li, Yiping Zhu, Daniel A. Keesler, J. Boelens, C. Dvorak, R. Agarwal, J. Auletta, R. Goyal, R. Hanna, K. Kasow, S. Shenoy, Angela R. Smith, M. Walters, M. Eapen   +19 more
semanticscholar   +1 more source

A Comparative Biochemical Study of Proteins Profile in Iraqi Children and Adolescent with ?-Thalassemia

Iraqi Journal of Pharmaceutical Sciences, 2017
The aim of the present research is to study different protein fractions in sera of children and adolescent with  β –thalassemia major and minor and to compare the results with that of healthy control.One hundred fifty children and adolescents were ...
Ali M. Malik, Emad M. Malik, Nawal MJ Al-Shammaa, Zeinab M. Al-Rubaei   +3 more
doaj   +3 more sources

Idiopathic Hypertriglyceridemia in Thalassemia Major: A Case Report [PDF]

National Journal of Laboratory Medicine, 2017
Thalassemia major is a severe hereditary haemolytic anaemia and is usually associated with normal serum lipid profile. But there are few reports in literature that hypertriglyceridemia can have an idiopathic association with β-thalassemia major.
Bhavya P Mohan, Prabhalekshmy KK, Letha V, Nisha TR   +3 more
doaj   +1 more source

The correlation between HLA class II and β-thalassemia major in Al-Karama teaching hospital

مجلة كلية الطب, 2016
Background: Thalassemia is a form of inherited autosomal recessive blood disorder characterized by abnormal formation of hemoglobin. Objective: Determine frequencies & association of HLA class II alleles (DRB1& DQB1) in Iraqi β-thalassemia major patients.
Sarmad M. Zeiny
doaj   +1 more source

An investigation of the effects of curcumin on iron overload, hepcidin level, and liver function in β‐thalassemia major patients: A double‐blind randomized controlled clinical trial

Phytotherapy Research, 2018
This study investigated the effects of curcumin, the active polyphenol in turmeric, on iron overload, hepcidin level, and liver function in β‐thalassemia major patients.
E. Mohammadi, A. Tamaddoni, D. Qujeq, E. Nasseri, F. Zayeri, H. Zand, M. Gholami, Seyed Mostafa Mir   +7 more
semanticscholar   +1 more source

Mutational analysis of the Janus kinase II (V617F) gene in patients with β-Thalassemia major

Zanco Journal of Pure and Applied Sciences, 2020
β-Thalassemia is a group of congenital hemolytic anemia that characterized by the underproduction of the indispensable hemoglobin molecule, the oxygen and carbon dioxide carrying protein inside the red cells.
Salar Adnan Ahmed
doaj   +3 more sources