Results 31 to 40 of about 5,627,179 (327)
BioMed Research International, 2019 Background Endocrinopathies are common in patients with β-thalassemia major despite parenteral iron chelation therapy with deferoxamine. Prevalence of abnormal glucose metabolism in previous studies was controversial. The aim of this study was to discuss
Li-Na He +9 more
semanticscholar +1 more source
Blood Advances, 2019 We studied 1110 patients with β-thalassemia major aged ≤25 years who received transplants with grafts from HLA-matched related (n = 677; 61%), HLA-mismatched related (n = 78; 7%), HLA-matched unrelated (n = 252; 23%), and HLA-mismatched unrelated (n ...
Chunfu Li +19 more
semanticscholar +1 more source
Thalassemia Reports, 2011 Bone marrow transplantation (BMT) is the only possible curative treatment for β-thalassemia major. The largest experience occurred in Pesaro, Italy, where the BMT was applied after a standard risk assessment.
S.S. Anak
doaj +1 more source
Efficacy of lactoferrin oral administration in the treatment of anemia and anemia of inflammation in pregnant and non-pregnant women: an interventional study [PDF]
, 2018 The discovery of the ferroportin-hepcidin complex has led to a critical review on the treatment of anemia and anemia of inflammation (AI). Ferroportin, the only known mammalian iron exporter from cells to blood, is negatively regulated by hepcidin, a ...
Antimo Cutone +6 more
core +2 more sources
Psychopathology in thalassemia major
Pediatrics International, 2009 AbstractBackground: Thalassemia major (TM) is a chronic disease with adverse emotional effects on both the child and the family. The aim of this study was to investigate the psychiatric state and behavioral problems of children with TM.Methods: Twenty children diagnosed with TM and 34 healthy children were enrolled in this study carried out by the ...
Polat, A. +4 more
openaire +6 more sources
The correlation between HLA class II and β-thalassemia major in Al-Karama teaching hospital
مجلة كلية الطب, 2016 Background: Thalassemia is a form of inherited autosomal recessive blood disorder characterized by abnormal formation of hemoglobin. Objective: Determine frequencies & association of HLA class II alleles (DRB1& DQB1) in Iraqi β-thalassemia major patients.
Sarmad M. Zeiny
doaj +1 more source
Identification of erythroferrone as an erythroid regulator of iron metabolism. [PDF]
, 2014 Recovery from blood loss requires a greatly enhanced supply of iron to support expanded erythropoiesis. After hemorrhage, suppression of the iron-regulatory hormone hepcidin allows increased iron absorption and mobilization from stores.
Ganz, Tomas +5 more
core +1 more source
Idiopathic Hypertriglyceridemia in Thalassemia Major: A Case Report [PDF]
National Journal of Laboratory Medicine, 2017 Thalassemia major is a severe hereditary haemolytic anaemia and is usually associated with normal serum lipid profile. But there are few reports in literature that hypertriglyceridemia can have an idiopathic association with β-thalassemia major.
Bhavya P Mohan +3 more
doaj +1 more source
Glycated Albumin as Marker for Early Hyperglycemia Detection in Adolescent with β Thalassemia Major
Indonesian Biomedical Journal, 2021 BACKGROUND: Hyperglycemia is one of the most common endocrine complications in children with β thalassemia major. Though the current diagnostic marker either requires fasting, has low reproducibility, or it is not an accurate for thalassemia patients ...
Dewinda Candrarukmi +2 more
doaj +1 more source
Serial echocardiographic left ventricular ejection fraction measurements: a tool for detecting thalassemia major patients at risk of cardiac death [PDF]
, 2013 Cardiac damage remains a major cause of mortality among patients with thalassemia major. The detection of a lower cardiac magnetic resonance T2* (CMR-T2*) signal has been suggested as a powerful predictor of the subsequent development of heart failure ...
Angastiniotis, M +21 more
core +1 more source