Results 161 to 170 of about 3,873 (265)

Contemporary Management of Thalassemia: A Perspective on Current Standards and the Emergence of FDA‐Approved Oral Therapy

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Thalassemia is an inherited hemoglobin disorder characterized by ineffective erythropoiesis, chronic anemia, and progressive multisystem complications that require lifelong management. Current treatment relies on regular red blood cell transfusions, iron chelation therapy, and supportive multidisciplinary care, while ...
Fnu Zainab, Abdul Haseeb Hasan, Muhammad Hafi Abid, Muhammad Ali Abid   +3 more
wiley   +1 more source

Distribution of Hemoglobin Variants: A Retrospective Study Based on Hemoglobin Electrophoresis Results From a University Hospital in Madagascar. [PDF]

Cureus
Fenomanana J, Rakotonjafiniarivo FH, Rasolozakandrainibe F, Niry Manantsoa S, Malalanirina AD, Ranaivosoa MK, Rakoto Alson AO.   +6 more
europepmc   +1 more source

Maternal and neonatal outcomes in Gaza amid armed hostilities in 2025

International Journal of Gynecology &Obstetrics, Volume 174, Issue 3, Page 1611-1620, September 2026.
Abstract Objective This study documents facility‐based maternal, obstetric, and neonatal outcomes and associated conflict‐related exposures and living conditions among pregnancy‐related encounters at Al‐Helou Maternity Hospital in Gaza from late April to early September 2025, with a small number of additional encounters recorded at Al‐Shifa Medical ...
Shaymaa Abuhaiba, Younis Elijla, Aya El‐Dadah, Othman Nassar, Meran Abu‐Sultan, Maysaa Almasry, Hebatallah Alkhatib, Mahmoud Alsady, Amir Mahdi Ghafarian, Muath Alsarafandi, Lina Abumughessib, Arham Ali, Yassar Arain, Abeerah Muhammad, Belal Aldabbour, Shayan Ali, Bilal Irfan   +16 more
wiley   +1 more source

Insights Into Hemoglobinopathies in Spain: A Comprehensive Review. [PDF]

EJHaem
Corrons JV.
europepmc   +1 more source

Unstable Hemoglobin, a Rare but Significant Cause of Hemolytic Anemia: Recognition of Peripheral Smear Findings Is Crucial for Diagnosis. [PDF]

Int J Lab Hematol
Shean RC, Agarwal A, Rets AV.
europepmc   +1 more source

Genome Editing for Glycogen Storage Diseases

Journal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
ABSTRACT Gene therapy has been developed for several glycogen storage diseases and has advanced into clinical trials. However, the limitations of these gene therapies with regard to stability following treatment early in life have led to the development of genome editing.
Troy von Beck, Raymond Wang, Dwight Koeberl   +2 more
wiley   +1 more source

Cerebral Blood Transit in Sickle Cell Anemia

Journal of Magnetic Resonance Imaging, Volume 64, Issue 3, Page 738-750, September 2026.
ABSTRACT Background Sickle cell anemia (SCA) patients upregulate cerebral blood flow to compensate for decreased arterial oxygen content. Such hyperemic conditions can manifest as venous hyperintense signal on arterial spin labeling (ASL) MRI, which may reflect faster capillary blood transit, altered oxygen extraction fraction (OEF), and infarct risk ...
Wesley T. Richerson, Megan A. Aumann, Alexander K. Song, Samantha Davis, Lauren Milner, Maria Garza, Dann Martin, L. Taylor Davis, Sumit Pruthi, Lori C. Jordan, Manus J. Donahue   +10 more
wiley   +1 more source

Emerging Technologies and Advanced Strategies in Hemoglobin Defect Screening. [PDF]

J Clin Med
Zhang C, Chen VC, Osa-Andrews B, Cao J.
europepmc   +1 more source

Smart Design: Integrating Artificial Intelligence and Gene Editing for Advanced mRNA Therapeutics

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
The challenges of mRNA therapy and the application of artificial intelligence and gene editing in the field of mRNA drugs. ABSTRACT Artificial intelligence (AI) and gene editing are increasingly being applied to the design and evaluation of mRNA therapeutics.
Haixing Shi, Shengbin Liu, Danni Dai, Shanhui Jiang, Tingchen Tian, Zhenyi Niu, Zhongzheng Xiang, Chaoyu Zou, Fang Liu, Xue Tang, Xin Jiang, Xiangrong Song   +11 more
wiley   +1 more source

Special Issue "Genetic Modifiers of Hemoglobinopathies: Recent Advances and Future Directions". [PDF]

Int J Mol Sci
Lederer CW, Felice AE, Kountouris P.
europepmc   +1 more source