Results 11 to 20 of about 4,160 (239)
Recent advances in β-thalassemias
Pediatric Reports, 2011 β-thalassemias, a group of autosomal recessive disorders resulting from reduced or absent production of β-globin chains from the β-globin locus, are very heterogeneous at the molecular level (for review see Weatherall & Clegg, 2001 and Cao & Galanello).1-
Antonio Cao, Paolo Moi, Renzo Galanello
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International Journal of Neonatal Screening, 2019 Thalassemia syndromes are among the most serious and common genetic conditions. They are indigenous in a wide but specific geographical area. However, through migration they are spreading across regions not previously affected. Thalassemias are caused by
Michael Angastiniotis, Stephan Lobitz
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CONCISE REVIEW ON THE FREQUENCY, MAJOR RISK FACTORS AND SURVEILLANCE OF HEPATOCELLULAR CARCINOMA (HCC) IN Β-THALASSEMIAS: PAST, PRESENT AND FUTURE PERSPECTIVES [PDF]
Mediterranean Journal of Hematology and Infectious Diseases, 2020 Due to the recent alarming increase in the incidence of hepatocellular carcinoma (HCC) in thalassemias, the aim of the present report is to review briefly the frequency, the major risk factors and the surveillance of HCC in β-thalassemias.
Vincenzo De Sanctis
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Indian Journal of Pathology and Microbiology, 2014 Background: The hereditary hemoglobin (Hb) disorders are the most commonly encountered single gene disorders in India. Data pertaining to the pattern of hemoglobinopathies and thalassemias is scarce in North East India, and hence it was considered ...
Mrinal Kumar Baruah +2 more
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Journal of Applied Hematology, 2014 Background: Thalassemias and hemoglobinopathies are highly prevalent in India. Identification of these disorders is important for epidemiologic purposes and for prevention of thalassemia major and clinically severe hemoglobinopathies. Objectives: The aim
Santosh Kumar Mondal +3 more
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Thalassemias. From gene to therapy
, 2021 Thalassemias (α, β, γ, δ, δβ, and εγδβ) are the most common genetic disorders worldwide and constitute a heterogeneous group of hereditary diseases characterized by the deficient synthesis of one or more hemoglobin (Hb) chain(s).
Nervi C. +11 more
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Thalassemia (Beta-Thalassemia)
International Journal For Multidisciplinary Research, 2023 Thalassemia is an inherited blood disorder characterized by less oxygen carrying protein (Haemoglobin) and fever red blood cells in the body than normal. There are mainly two types of thalassemia i.e. Alpha and Beta thalassemia about 1-5% of the global population 80-90 million people are the carrier of ß thalassemia which is major concern.
Tathe Pratiksha Annasaheb - +2 more
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Hemoglobin genes; Sickle-cell anemia - Thalassemias [PDF]
, 2009 Educational Items on Hemoglobin genes; Sickle-cell anemia ...
Huret, JL, Troussard, X
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Progress toward the control and management of the thalassemias [PDF]
, 2016 Because of the particular high frequency of different severe forms of both and thalassemia in Asia the development of approaches for their prevention and management is particularly challenging.
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Journal of Applied Hematology, 2017 Background: Beta thalassemias are a group of hereditary blood disorders that are characterized by reduction or complete absence of the β-globin chain synthesis due to mutations, affecting critical areas of the β-globin gene on the chromosome 11.
Ayman Mashi +4 more
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