Results 221 to 230 of about 3,873 (265)
Some of the next articles are maybe not open access.
Pediatric Clinics of North America, 2013
The thalassemia syndromes are hemoglobin disorders that result from significantly reduced or absent synthesis of either the α- or β-globin chains. The result is a chronic hemolytic anemia with ineffective erythropoiesis and bone marrow overstimulation.
Alissa, Martin, Alexis A, Thompson
openaire +2 more sources
The thalassemia syndromes are hemoglobin disorders that result from significantly reduced or absent synthesis of either the α- or β-globin chains. The result is a chronic hemolytic anemia with ineffective erythropoiesis and bone marrow overstimulation.
Alissa, Martin, Alexis A, Thompson
openaire +2 more sources
Hemoglobin, 2022
Indonesia is located along the 'Thalassemia Belt' and a hotspot for hemoglobinopathies. Around 3.0-10.0% of the population carry β-thalassemia (β-thal) and 2.6-11.0% of the population carry α-thalassemia (α-thal). It is estimated that around 2500 babies are born with β-thal major (β-TM) each year.
Pustika A. Wahidiyat +8 more
openaire +2 more sources
Indonesia is located along the 'Thalassemia Belt' and a hotspot for hemoglobinopathies. Around 3.0-10.0% of the population carry β-thalassemia (β-thal) and 2.6-11.0% of the population carry α-thalassemia (α-thal). It is estimated that around 2500 babies are born with β-thal major (β-TM) each year.
Pustika A. Wahidiyat +8 more
openaire +2 more sources
The Journal of Bone & Joint Surgery, 1976
Fractures occur frequently in patients with homozygous beta-thalassemia. A study was made of the fractures noted in a group of patients who were followed at the Thalassemia Clinic at The New York Hospital-Cornell Medical Center. Results indicate that these patients often sustain fractures which are multiple and which frequently heal with resultant ...
D M, Dines, V C, Canale, W D, Arnold
openaire +2 more sources
Fractures occur frequently in patients with homozygous beta-thalassemia. A study was made of the fractures noted in a group of patients who were followed at the Thalassemia Clinic at The New York Hospital-Cornell Medical Center. Results indicate that these patients often sustain fractures which are multiple and which frequently heal with resultant ...
D M, Dines, V C, Canale, W D, Arnold
openaire +2 more sources
Hemoglobin, 2022
Thailand has a population of 66.2 million with 30.0-40.0% of them carrying thalassemia genes. Interaction of these thalassemia genes lead to more than 60 genotypes with a wide spectrum of clinical severity from asymptomatic to lethal. Estimation based on gene frequencies and number of babies born each year, there will be about 1.2% babies born with ...
Kittiphong Paiboonsukwong +3 more
openaire +2 more sources
Thailand has a population of 66.2 million with 30.0-40.0% of them carrying thalassemia genes. Interaction of these thalassemia genes lead to more than 60 genotypes with a wide spectrum of clinical severity from asymptomatic to lethal. Estimation based on gene frequencies and number of babies born each year, there will be about 1.2% babies born with ...
Kittiphong Paiboonsukwong +3 more
openaire +2 more sources
Hemoglobin, 2022
The estimated population of Pakistan is approximately 225,633,392 (225 million). The healthcare delivery system of Pakistan is complex because it includes healthcare subsystems operated by both the federal government and the provincial government. In Pakistan β-thalassemia (β-thal) trait frequency ranges between 5.0-7.0%, thus, there are more than 10 ...
openaire +2 more sources
The estimated population of Pakistan is approximately 225,633,392 (225 million). The healthcare delivery system of Pakistan is complex because it includes healthcare subsystems operated by both the federal government and the provincial government. In Pakistan β-thalassemia (β-thal) trait frequency ranges between 5.0-7.0%, thus, there are more than 10 ...
openaire +2 more sources
American Journal of Hematology, 1977
AbstractThe current concepts of α‐thalassemia including incidence, genetics, clinical spectrum and diagnosis are reviewed. Speculation concerning clinical application of the molecular biology of α‐thalassemia is also presented.
J G, Adams, M H, Steinberg
openaire +2 more sources
AbstractThe current concepts of α‐thalassemia including incidence, genetics, clinical spectrum and diagnosis are reviewed. Speculation concerning clinical application of the molecular biology of α‐thalassemia is also presented.
J G, Adams, M H, Steinberg
openaire +2 more sources
Blood, 1956
Abstract 1. The incidence of Thalassemia minor in the Sikh community of Vancouver, Canada, was computed to be six per cent from a study of 80 individuals, of whom five showed this condition. 2. To determine the incidence in blood relatives, the families of the above five propositi were then studied in detail.
J K, SIDDOO +4 more
openaire +2 more sources
Abstract 1. The incidence of Thalassemia minor in the Sikh community of Vancouver, Canada, was computed to be six per cent from a study of 80 individuals, of whom five showed this condition. 2. To determine the incidence in blood relatives, the families of the above five propositi were then studied in detail.
J K, SIDDOO +4 more
openaire +2 more sources
Hematology/Oncology Clinics of North America, 2023
Edward J, Benz, Vijay G, Sankaran
openaire +2 more sources
Edward J, Benz, Vijay G, Sankaran
openaire +2 more sources
Pathophysiology of thalassemia
Current Opinion in Hematology, 2002Despite discoveries concerning the molecular abnormalities that led to the thalassemic syndromes, it still is not known how accumulation of excess unmatched alpha-globin in beta thalassemia and beta-globin in alpha thalassemia leads to red blood cell hemolysis in the peripheral blood, and in the beta thalassemias particularly, premature destruction of ...
openaire +2 more sources