Results 121 to 130 of about 42,998 (266)

THC [PDF]

open access: yes, 2019
openaire   +1 more source

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology

open access: yesBritish Journal of Pharmacology, EarlyView.
Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley   +1 more source

Cannabinoid CB1 allosteric ligands suppress inflammatory pain in male mice without tolerance, motor impairment, memory deficits or respiratory depression

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Positive allosteric modulators (PAMs) engage sites distinct from the orthosteric CB1 cannabinoid receptor binding site. GAT211, a racemic ligand, contains GAT228 (R) and GAT229 (S) enantiomers. Whether enantiomer‐mediated differences in allosteric activation or positive allosteric modulation translate into differences in
Ifeoluwa D. Solomon   +3 more
wiley   +1 more source

Deep Residual Combiner: A Learned Fusion of Spatial, Temporal, and Multiscale Correlated Pixel Estimates

open access: yesComputer Graphics Forum, EarlyView.
Abstract Correlation‐based rendering techniques continue to advance, and efficiently exploiting correlations between pixel estimates has become increasingly important. The deep combiner framework [BHHM20] allows us to fuse independent and correlated pixel estimates but focuses solely on spatial correlations.
W. Zhou, E. Hughes, T. Hachisuka
wiley   +1 more source

Comprehensive Profiling of Phytocannabinoids and Semisynthetic Cannabinoids in Seized Materials from Northern Italy. [PDF]

open access: yesACS Omega
Casati S   +13 more
europepmc   +1 more source

Mixed Super‐Circles

open access: yesComputer Graphics Forum, EarlyView.
Abstract We introduce mixed super‐circles, a position‐curvature formulation of the original dynamic 2D super‐helix model. Compared to the latter, purely curvature‐based model – the so‐called chained formulation –, the mixed formulation that we propose here drastically reduces the algorithmic complexity of the solving scheme – from quadratic to quasi ...
Emile Hohnadel   +2 more
wiley   +1 more source

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