Results 91 to 100 of about 583,007 (361)

Analysis of ozone and nitric acid in spring and summer Arctic pollution using aircraft, ground-based, satellite observations and MOZART-4 model: source attribution and partitioning [PDF]

, 2012
In this paper, we analyze tropospheric O_3 together with HNO_3 during the POLARCAT (Polar Study using Aircraft, Remote Sensing, Surface Measurements and Models, of Climate, Chemistry, Aerosols, and Transport) program, combining observations and model ...
Batchelor, R. L., Clerbaux, C., Coffey, M. T., Coheur, P. -F., Crounse, J. D., Edwards, D. P., Emmons, L., Hannigan, J., Hurtmans, D., Lindenmaier, R., Nowak, J. B., Ryerson, T. B., Saunois, M., Strong, K., Weinheimer, A. J., Wennberg, P. O., Wespes, C.   +16 more
core   +4 more sources

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

“The prayer circles in the air”: a qualitative study about traditional healer profiles and practice in Northern Norway

International Journal of Circumpolar Health, 2018
In Northern Norway, traditional healing has been preserved by passing down the knowledge through generations. Religious prayers of healing (reading) and Sami rituals (curing) are examples of methods that are used.
Anette Langås-Larsen, Anita Salamonsen, Agnete Egilsdatter Kristoffersen, Trine Stub   +3 more
doaj   +1 more source

Foxes and food subsidies: anthropogenic food use by red and Arctic foxes, and effects on Arctic fox survival, on the Arctic Coastal Plain of Alaska [PDF]

, 2013
Thesis (M.S.) University of Alaska Fairbanks, 2013Food subsidies have the potential to impact wildlife on the Arctic Coastal Plain of Alaska. Red foxes (Vulpes vulpes (L., 1758)) expanded their range into Arctic regions during the 20th century, and the ...
Savory, Garrett
core  

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Sami yoik, Sami history, Sami health: a narrative review

International Journal of Circumpolar Health, 2018
Music as a possible health-promoting agent has attained increasing academic and scientific interest over the last decades. Nonetheless, possible connections between indigenous singing traditions and health beyond traditional ceremonial healing practices ...
Soile Hämäläinen, Frauke Musial, Anita Salamonsen, Ola Graff, Torjer A. Olsen   +4 more
doaj   +1 more source

Arctic–CHAMP: A program to study Arctic hydrology and its role in global change [PDF]

, 2002
The Arctic constitutes a unique and important environment that is central to the dynamics and evolution of the Earth system. The Arctic water cycle, which controls countless physical, chemical, and biotic processes, is also unique and important.
Bromwhich, David, Hamilton, Lawrence C., Hinzman, Larry, Morison, James, Peterson, Bruce, Romanovsky, Vladimir, Sturm, Matthew, Vorosmarty, Charles J., Webb, Robert   +8 more
core   +1 more source

The Arctic Expedition [PDF]

Nature, 1875
THE absence of sunlight during the Arctic winter is said to have an injurious effect on the health of both men and dogs; yet it does not appear that the best substitute for solar light has ever been employed for illuminating purposes during the dark season.
openaire   +3 more sources