Results 51 to 60 of about 69,417 (298)
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Molecules, 2023 Total synthesis of the 2-formylpyrrole alkaloid hemerocallisamine I is presented, both in racemic and enantiopure form. Our synthetic strategy involves (2S,4S)-4-hydroxyglutamic acid lactone as the key intermediate.
Lucia Pinčeková +5 more
doaj +1 more source
, 2012 The anticipated performance of calorimeter crystals in the environment expected after the planned High-Luminosity upgrade of the Large Hadron Collider (HL-LHC) at CERN has to be well understood, before informed decisions can be made on the need for ...
Dissertori, G. +7 more
core +2 more sources
Highly-crystallized quaternary chalcopyrite nanocrystals via a high-temperature dissolution–reprecipitation route [PDF]
, 2011 Quaternary chalcopyrite (Cu2CoSnS4, Cu2ZnSnS4) nanocrystals displaying high crystallization and controlled morphology were synthesized via a high-temperature growth regime achieved by dissolution–reprecipitation of tailored ultrafine precursors in the ...
Balocchi, Andréa +4 more
core +2 more sources
On the Electronic Structures of the M-Centers in Alkali-halide Crystals [PDF]
Progress of Theoretical Physics, 1952 The electronic energy levels of the M-centers in the colored LiCI and NaCl crystals are calculated by LCAO method, assuming Seitz's model. The ground state and the first excited state (optically permitted) are shown to belong to A, and B, symmetry, respectively, the wave-lengths of the optical transition between them being in comparatively good ...
T. Inui, Y. Uemura, Y. Toyozawa
openaire +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Mechanisms of influence of modifiers on crystallization of tin and aluminium bronzes
Литьë и металлургия, 2023 It has been shown that elementary crystalline cells of α‑phases of tin, aluminum bronzes and main modifying phases do not correspond to the principle of structural and dimensional correspondence of Dankov‑Konobeevsky.
E. I. Marukovich +2 more
doaj +1 more source
The decoherence criterion [PDF]
, 2001 The decoherence mechanism signals the limits beyond which the system dynamics approaches the classical behavior. We show that in some cases decoherence may also signal the limits beyond which the system dynamics has to be described by quantum field ...
ELEONORA ALFINITO +4 more
core +2 more sources
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source