Results 41 to 50 of about 1,755 (247)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Centers of crystallization in antimony thin films studied by transnission electron microscopy [PDF]
, 2019 We performed TEM studies of 7 crystallization centers using specially evaporated Sb thin films in finite areas. Strong internal lattice bending is revealed by use of the bend contour method.Partial support of project 3.6121.2017/8.9 (RF Ministry of ...
Kolosov, V. Yu. +3 more
core
Formation of microstructure of Bi-40 wt. % Sn alloy during hightspeed crystallization [PDF]
Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2017 Rapidly solidified foils of Bi — 40 wt. % Sn have homogeneous distribution bismuth and tin phases with microcrystalline structure. Its formation is caused by the spinodal decay of supercooled supersaturated liquid solution and subsequent nucleation and ...
V.G. Shepelevich
doaj +1 more source
About modification of foundry magnesium alloys
Литьë и металлургия, 2023 It is shown that the main modifiers of foundry magnesium alloys cannot create heterogeneous crystallization centers in melts during their solidification. Modification of alloy structures is an adsorption‑nanostructural process.
E. I. Marukovich +2 more
doaj +1 more source
Growth Rate of Crystal Surfaces with Several Dislocation Centers [PDF]
Crystal Growth & Design, 2018 We study analytically and numerical the growth rate of a crystal surface growing by several screw dislocations. To describe several spiral steps we use the revised level set method for spirals by the authors (Journal of Scientific Computing 62, 831-874, 2015).
Takeshi Ohtsuka +2 more
openaire +3 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
About the thermodynamics aspect of crystallization of amorphous metals
, 2009 Приведены данные моделирования методом молекулярной динамики, которые свидетельствуют о том, что структура малых нанокристаллов очень несовершенна, изменчива. Скорость роста малых центров кристаллизации сильно зависит от их размера.
Овруцкий, А.М. +1 more
core +3 more sources
Molecules, 2023 Total synthesis of the 2-formylpyrrole alkaloid hemerocallisamine I is presented, both in racemic and enantiopure form. Our synthetic strategy involves (2S,4S)-4-hydroxyglutamic acid lactone as the key intermediate.
Lucia Pinčeková +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source