Results 101 to 110 of about 299,168 (307)

Aspects of Urban Military Organisation in the Late Middle Ages and Early Modern Period: The Case of Freiburg i. Ue. (c. 1440-1500)

open access: yes, 2020
My research looks into the institutional, operational and material aspects of medieval towns’ military organisation. The research is concentrated on (what is today) the French speaking part of Switzerland – the so-called Romandie.
Roelofsen, Mathijs Christian   +1 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Chastity, bachelorhood and masculinity in early modern Europe : the case of the Hospitaller Knights of St. John (c. 1520- c. 1650) [PDF]

open access: yes, 2009
This chapter engages with gender through an analysis of the historiography of chastity, bachelorhood and masculinity in early modern Europe. We begin with an overview of the ideas and practices related to chastity during the Middle Ages and how these ...
Buttigieg, Emanuel
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Land and Sea in the Early Middle Ages

open access: yes, 2012
Du 27 au 28 avril 2012. University of Queensland, Brisbane, Australie The Australian Early Medieval Association This conference addresses the theme of LAND and SEA in the Early Medieval World, ca. 300-1100.
administrateur
core  

Desiring the east: a comparative study of Middle English romance and modern popular sheikh romance [PDF]

open access: yes, 2012
This thesis comparatively examines a selection of twenty-first century sheikh romances and Middle English romances from the fourteenth and fifteenth centuries that imagine an erotic relationship occurring between east and west.
Burge, Amy
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Anglo-Saxon and Arabic Identity in the Early Middle Ages

open access: yes, 2019
This dissertation reassesses and reframes current discourses of Orientalisms and post-colonialisms via analysis of Old English and Arabic texts of the early Middle Ages as well as Latin and Biblical Hebrew texts.
Lennington, David Kent
core   +1 more source

Preface: Special Issue “Geoarchaeology and past human–environment interactions” [PDF]

open access: yesEiszeitalter und Gegenwart, 2020
H. von Suchodoletz   +5 more
doaj   +1 more source

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