Results 111 to 120 of about 299,168 (307)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
An Agglomeration of Early Middle Ages: Meda'in
, 2014 The group of the cities of Meda'in, the administrative capital of the Sassanid Empire from the early Middle Ages to the collapse of this empire, is one of the biggest metropolises of the antiquity and of the Middle Ages. The group of the cities of Meda'in, consisting of many cities and towns built in different sizes and various times, has a diverse ...
Bakir, Abdulhalik, Altungök, Ahmet
openaire +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Archaeological research into the periods following the Early Middle Ages in Slovenia
Arheološki Vestnik, 2010 The authors outline the archaeological research into the periods following the Early Middle Ages in Slovenia, from its beginnings in the late 19th centur y up to the present.
Katarina Predovnik, Tomaž Nabergoj
doaj
The modern origins of the early Middle Ages /
, 2013 "[The book's] subject matter is the changing interpretation within Europe of the end of the Roman Empire and the early Middle Ages from the eighteenth century to the present and how individual interpretations influenced and were influenced by the ...
Wood, Ian N.(viaf)262538825
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Architecture of Lovran in the late Middle Ages and early modern period
Zbornik Lovranšćine, 2010 Based on the review of existing studies on urbanism and architecture of Lovran, on meticulous field work and analysis of both published and unpublished graphic sources, new observations on the architecture of the old town of Lovran, its settlement and ...
Marijan Bradanović
doaj
CULTURAL AND INTELLECTUAL SPACE OF THE EARLY MIDDLE AGES: THE PHENOMENON OF BOETHIUS
Епістемологічні дослідження у філософії, соціальних і політичних наукахThe specificity of the cultural and intellectual space of the early Middle Ages is explored through the prism of the activity of Anicius Manlius Severinus Boethius. The phenomenon of Boethius individuality and creativity is viewed as the primary element
Вікторія ВЕРШИНА
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Findings of Ritual Spoons of the Early Middle Ages in the Oka-Sviyaga Interfluve
Поволжская археология, 2016 The article discusses medieval ritual spoons found on the territory between the Oka and Sviyaga rivers, so far quite poorly studied. These fi nds, especially in the context of funerary complexes, supplement our knowledge of the pagan cults practiced by ...
Grishakov Valeriy V. +2 more
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