Results 121 to 130 of about 299,168 (307)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The early development of the cult of St Katherine of Alexandria with particular reference to England

open access: yes, 2003
PhDSt Katherine of Alexandria, traditionally martyred c. 305, became one of the most popular saints of the later Middle Ages. Whilst most modem studies concentrate on the period of the cult's greatest popularity in the fourteenth and fifteenth ...
Walsh, Christine Louise
core  

Do we live in Cities in the Early Middle Ages: the difficult question of house remains

open access: yes, 2023
International audienceIn Western Europe, the question of the material reality of cities during the early Middle Ages has been debated for many years. While religious buildings are well documented by both texts and archaeology and funerary discoveries are
Lefebvre, Bastien
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Review of the book: Bogachev A.V., Frantsuzov D.A. Costume of the proto–Bulgars of the Middle Volga region: the end of the VII – the beginning of the X century (Samara, 2012, 350 p.)

open access: yesПоволжская археология, 2014
Methodological and source study aspects of the research devoted to the costume of early medieval cattle-breeding population of the Middle Volga region carried out in the monograph by A.V. Bogachev and D.A. Frantsuzov are examined in the review.
Liphanov Nikolay A.
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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