Results 121 to 130 of about 128,359,238 (287)

Findings of Ritual Spoons of the Early Middle Ages in the Oka-Sviyaga Interfluve

open access: yesПоволжская археология, 2016
The article discusses medieval ritual spoons found on the territory between the Oka and Sviyaga rivers, so far quite poorly studied. These fi nds, especially in the context of funerary complexes, supplement our knowledge of the pagan cults practiced by ...
Grishakov Valeriy V.   +2 more
doaj   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Emotion, violence, vengeance and law in the Middle Ages : essays in honour of William Ian Miller /

open access: yes, 2018
Emotion, violence, vengeance, and law in Medieval Historical Sources -- Hot anger and just indignation: Justificatory strategies in Early Modern German homicide trials / Susanne Pohl-Zucker -- Trial by ordeal by jury in Medieval England, or Saints and ...
Gilbert, Kate,edt   +1 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Precision Lost Wax Casting

open access: yesEXARC Journal, 2012
The limits of precision casting were explored experimentally at the Bronze Casting Workshop at Wilhelminaoord, the Netherlands, by making wax models, moulds and lost wax castings using essentially early metalworking conditions.
Nigel Meeks   +2 more
doaj  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Texts and Identities in the Early Middle Ages

open access: yesBulletin du Centre d’Études Médiévales d’Auxerre, 2008
Régine Le Jan
doaj   +1 more source

Review of the book: Bogachev A.V., Frantsuzov D.A. Costume of the proto–Bulgars of the Middle Volga region: the end of the VII – the beginning of the X century (Samara, 2012, 350 p.)

open access: yesПоволжская археология, 2014
Methodological and source study aspects of the research devoted to the costume of early medieval cattle-breeding population of the Middle Volga region carried out in the monograph by A.V. Bogachev and D.A. Frantsuzov are examined in the review.
Liphanov Nikolay A.
doaj  

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