Results 91 to 100 of about 7,085,195 (293)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Apropierea și întârzierea parousiei la părinții ante- și post-niceeni – partea a II-a

open access: yesTheoRhēma, 2016
The concepts of the nearness and delay of parusia in the thought of the ante- and post-Nicene Fathers, dealt with in part one, have here been taken up again, this time with a focus on the way the Nicene and post-Nicene Fathers related to the nearness ...
Laurențiu Moț
doaj   +2 more sources

Female Brazilian Diaspora during The End of the World: Decolonial Narratives in Germany and Spain

open access: yesLL Journal
Las trayectorias personales o repertorios biográficos desempeñan un papel crucial en la configuración del repertorio lingüístico de un individuo. Mi investigación se propone profundizar en este fenómeno dentro de un contexto social, examinando las ...
Miriam Lange
doaj  

World's end

open access: yes, 2020
Coverage: Murang ...
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Towards Data-driven Simulation of End-to-end Network Performance Indicators

open access: yes, 2019
Novel vehicular communication methods are mostly analyzed simulatively or analytically as real world performance tests are highly time-consuming and cost-intense.
Sliwa, Benjamin, Wietfeld, Christian
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

DoShiCo Challenge: Domain Shift in Control Prediction

open access: yes, 2018
Training deep neural network policies end-to-end for real-world applications so far requires big demonstration datasets in the real world or big sets consisting of a large variety of realistic and closely related 3D CAD models. These real or virtual data
Kelchtermans, Klaas, Tuytelaars, Tinne
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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