Results 101 to 110 of about 186,902,381 (301)
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
43 p.This comprehensive index of all issues between 1975 and the end of 1990 replaces and up-dates the World health index 1975-1987 ...
World Health Organization
core
Although some of the authors of the relevant literature believe that the phrase “cultural imperialism” is a subtle, “soft” form of domination, which does not involve an open, visible or military political control (in realistic terms), other scholars ...
Mădălina Virginia ANTONESCU
doaj
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
28 p.The comprehensive index of all issues between 1975 and the end of 1987 replaces and up-dates the World health index 1958-1983 ...
World Health Organization
core
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
1. Headlines (00:00-00:28)2. Europe puts together its response to the World Trade Organisation and Jamaica says it is time to create a marketing plan for Caribbean bananas. Industry and Commerce Minister of State Philip Powell is interviewed and Caroline
Rickerson, Bruce (interviewee) +7 more
core
Saint Lucia's Prime Minister John Compton has spoken out to try and offset a national strike by the country's most powerful trade unions. Dominica's Prime Minister Dame Eugenia Charles has difficulties accepting the allegations which seek to implicate ...
The British Broadcasting Corporation +8 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
In Saint Lucia, a grouping of six major unions have voted to go ahead with two days of strike action. Trinidad and Tobago's Minister of Foreign Affairs, Ralph Maraj has been fired. Mr. Maraj contemplates his political future after the announcement.
Cross, Ulric (interviewee) +7 more
core

