We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Inumana intertestualità: appunti sulla citazione nelle Poesie della fine del mondo
Delfini’s way of writing is often tinged with intertextual quotations or allusions which prove to be functional within his work. In particular, the Poesie della fine del mondo, where the phenomenon acquires a status of unprecedented importance, are ...
Gian Luca Picconi
doaj
Descartes on the Infinity of Space vs. Time [PDF]
In two rarely discussed passages – from unpublished notes on the Principles of Philosophy and a 1647 letter to Chanut – Descartes argues that the question of the infinite extension of space is importantly different from the infinity of time.
Gorham, Geoffrey
core
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Pandemic scientific data sharing recommendations: examining and re-imagining pre-print servers after the end of the world-wide emergency. [PDF]
Doron S, Branch-Elliman W.
europepmc +1 more source
The More You Know: Using Knowledge Graphs for Image Classification
One characteristic that sets humans apart from modern learning-based computer vision algorithms is the ability to acquire knowledge about the world and use that knowledge to reason about the visual world.
Gupta, Abhinav +2 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A wise person plants a tree a day before the end of the world: coping with the emotional experience of climate change in Poland. [PDF]
Zaremba D +9 more
europepmc +1 more source
An exploratory study to design an adaptive hypermedia system for online-advertisement [PDF]
The revolutionary world of the World Wide Web has created an open space for a multitude of fields to develop and propagate. One of these major fields is advertisement.
Al Qudah, Dana +2 more
core

