Results 91 to 100 of about 2,682,280 (287)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Designing a tool/platform for developing expert systems
Taikomieji Moksliniai TyrimaiThe article analyzes the company's need to create a prototype for the development of expert systems. Expert systems and tools for their creation were examined, functions and software for the creation of an expert system that met the needs of the company ...
Donatas Daugirdas, Karolis Paliliūnas
doaj +1 more source
USING DATABASES TO DESIGN BEARINGS EMPLOYED IN THE CONSTRUCTION OF MECHANISMS [PDF]
Fiabilitate şi Durabilitate, 2018 Designing the knowledge database of an expert system is a difficult task that requires a close cooperation between a human expert and the knowledge engineer.
Anca-Olimpia MOSNEAGA, Iosif TEMPEA
doaj
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Expert system in domain of energy efficiency and failure detection in process industry [PDF]
Journal on Processing and Energy in Agriculture, 2015 Expert systems are very suitable for fault detection because they are easy to develop, have capability to reason under uncertainty and the capability to deliver explanations for the solutions provided.
Petković Milena +3 more
doaj
A center for commercial development of space: Real-time satellite mapping. Remote sensing-based agricultural information expert system [PDF]
The research project results in a powerful yet user friendly CROPCAST expert system for use by a client to determine the crop yield production of a certain crop field.
Diaz, Carlos F. +2 more
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
PCLIPS (Parallel CLIPS) is a set of extensions to the C Language Integrated Production System (CLIPS) expert system language. PCLIPS is intended to provide an environment for the development of more complex, extensive expert systems.
Gryphon, Coranth D., Miller, Mark D.
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Expert system technology [PDF]
The expert system is a computer program which attempts to reproduce the problem-solving behavior of an expert, who is able to view problems from a broad perspective and arrive at conclusions rapidly, using intuition, shortcuts, and analogies to previous ...
Prince, Mary Ellen
core +1 more source