Results 51 to 60 of about 980,468 (308)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Closed form metrics to accurately model the response in general arbitrarily-coupled RC trees. [PDF]
, 2003 Closed form expressions are presented for the first and second moment of the impulse response for arbitrarily-coupled RC trees with multiple drivers, and used to generate accurate second order estimations of the transfer function from any driver to the ...
Elassaad, Shauki +2 more
core +1 more source
Energies, 2017 A transformer is the most valuable and expensive property for power utility, thus ensuring its reliable operation is a major task for both operators and researchers.
Zhongyong Zhao +5 more
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Interdependensi Variabel Makro Ekonomi terhadap Perkembangan Aset Perbankan Syariah
Al-Ulum, 2017 This article aims to analyse the macroeconomic interdependence and development of sharia banking assets in Indonesia. This study employed quantitative method by using Vector Auto Regression (VAR) technique.
Noni Rozaini +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Evaluation of measurement uncertainty for time-dependent quantities
EPJ Web of Conferences, 2014 One of the main challenges in the analysis of dynamic measurements is the estimation of the timedependent value of the measurand and the corresponding propagation of uncertainties.
Eichstä Sascha +3 more
doaj +1 more source
Application of Machine Learning for the Spatial Analysis of Binaural Room Impulse Responses
Applied Sciences, 2018 Spatial impulse response analysis techniques are commonly used in the field of acoustics, as they help to characterise the interaction of sound with an enclosed environment.
Michael Lovedee-Turner, Damian Murphy
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source