Results 71 to 80 of about 1,794,418 (319)
Human islet amyloid polypeptide at the air-aqueous interface: a Langmuir monolayer approach
, 2012 Human islet amyloid polypeptide (hIAPP) is the source of the major component of the amyloid deposits found in the islets of Langerhans of around 95 per cent type 2 diabetic patients.
Whyte, Jeffrey D +4 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Product–process interface for manufacturing data management as a support for DFM and virtual manufacturing [PDF]
, 2008 This research work was supported by SNECMA as part of the MAIA ( http://www.le-webmag.com/article.php3?id_ article=2&lang=) project, the Region Champagne-Ardennes and Sisson Lehmann of the Wheelabrator group.In order to tackle a continuous improvement of
Jawhar Elgueder +8 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Journal of Synchrotron RadiationTransition-metal nitrogen-doped carbons (TM-N-C) are emerging as a highly promising catalyst class for several important electrocatalytic processes, including the electrocatalytic CO2 reduction reaction (CO2RR).
Andrea Martini +6 more
doaj +1 more source
Variable power singular interface elements for a crack normal to the bimaterial interface
, 1994 Zero thickness crack tip interface elements for a crack normal to the interface between two materials are presented. The elements are shown to have the desired r(lambda-1) (0 < lambda < 1) singularity in the stress field at the crack tip and are ...
吴永礼 +1 more
core +1 more source
A multi-level interface model for damaged masonry [PDF]
, 2013 The aim of the present work is to propose a new micro-mechanical model in the context of the deductive approach used to derive interface models. This model, based on a previous study introduced previously by A. Rekik and F.
E. Sacco +7 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
You got to coordinate, stably: 3D bimanual guidance with haptic and auditory cues
Frontiers in Virtual RealityNon-visual motor guidance is essential for expert hands-on tasks, where visual attention must remain focused on the workspace. However, conveying complex 3D spatial information through wearable haptics remains a challenge due to limited resolution and ...
Takashige Suzuki +3 more
doaj +1 more source