Results 81 to 90 of about 127,858,707 (311)
Variable power singular interface elements for a crack normal to the bimaterial interface
, 1994 Zero thickness crack tip interface elements for a crack normal to the interface between two materials are presented. The elements are shown to have the desired r(lambda-1) (0 < lambda < 1) singularity in the stress field at the crack tip and are ...
吴永礼 +1 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
An Application-Specific Ad Hoc Query Interface
, 1992 An application specific database browser is described that allows end-users to express ad hoc queries that include geometric, scientific, and business data.
Brian Smith, Query Interface
core
Human islet amyloid polypeptide at the air-aqueous interface: a Langmuir monolayer approach
, 2012 Human islet amyloid polypeptide (hIAPP) is the source of the major component of the amyloid deposits found in the islets of Langerhans of around 95 per cent type 2 diabetic patients.
Whyte, Jeffrey D +4 more
core +1 more source
Nature Chemistry, 2015 Porphyrins and other tetrapyrrole macrocycles possess an impressive variety of functional properties that have been exploited in natural and artificial systems. Different metal centres incorporated within the tetradentate ligand are key for achieving and regulating vital processes, including reversible axial ligation of adducts, electron transfer ...
Willi Auwärter +3 more
openaire +3 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Characterization and modelling of moisture driven interface failures
, 2004 Since moisture sensitivity level (MSL) tests are part ofthe international reliability qualification standards, all the microelectronics components/products have to pass these specifications.
Driel, WD Willem van +9 more
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Transforming graphical interfaces into auditory interfaces
Conference companion on Human factors in computing systems - CHI '95, 1995 This work explores transforming graphical interfaces into auditory interfaces. By transparently transforming graphical application written with a commercial toolkit, I have been able to investigate strategies for generically modeling graphical interfaces.
openaire +1 more source