Results 101 to 110 of about 629,141 (310)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
"The meaning of life is to give life meaning"
, 2022 Tema: Temaet for denne oppgaven omhandler hvordan opplevelse av mening i livet kan påvirke helse og livskvalitet. I denne sammenheng undersøkes det også hvordan aktiviteter i hverdagen og sosiodemografi kan virke inn i dette samspillet.
Engvig, Jan Petter
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Impact of the sense of life meaning of nurses in oncology department on the quality of work life
Huli yanjiu, 2022 ObjectiveTo discuss the impact of the sense of life meaning of oncology nurses on their quality of working life（QWL）.MethodsIn July 2021，a total of 177 nurses in the oncology department were enrolled from 3 tertiary grade A hospitals in Dalian by the ...
TU Shuhan +3 more
doaj
, 2016 Chinese adolescents’ academic achievement has been much researched while relatively little is known about their personal growth such as attaining a sense of meaning in life.
Meilin Guan, Yongjuan Li, Qian Wang
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
When the man is born the whole world is looking forward to it, and only him is crying, and it should live in a way when he dies the whole world is crying, and only him is looking forward to it [PDF]
Baština, 2016 Man as the only conscious being has a need to search for the meaning of life to penetrate into the search for the meaning of life and depths of becoming and eagerly seeks all that is immortal in it.
Nedeljković Radica M.
doaj
The Immortal, the Intrinsic and the Quasi Meaning of Life
, 2015 Through the examination of the lives (or afterlives) of several immortal beings, this paper defends a version of Moritz Schlick’s claim that the meaning of life is play.
Rowlands, Mark
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source