Results 111 to 120 of about 629,141 (310)
Transculturalism and the Meaning of Life
Humanities, 2016 I begin by introducing the standoff between the transculturalist aim of moving beyond cultural inheritances, and the worry that this project is itself a product of cultural inheritances.
James Tartaglia
doaj +1 more source
Objectives. This study is relevant to understanding the quality of life (QOL) among elderly individuals in Romania. With an increasing aging population, it is crucial to examine the factors contributing to older adults' well-being and life satisfaction ...
Florin-Marius VOICU
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Comparative Study of the Relation between Death and Dmmortality and the Meaning of Life in Tolstoy and Molla Sadra [PDF]
حکمت صدرایی, 2017 The problem of the relation between death and immortality on the meaning of life in the authorities of thinkers such as Tolstoy and Mulla Sadra has been considered as one of the fundamental issues. Once Tolstoy felt absurdity, decided to find a solution.
sadi saffari +2 more
doaj
, 2013 Review of the following book: Sigurður Árni Þórðarson, Limits and Life: Meaning and Metaphors in the Religious Language of Iceland (Peter Lang: American University Studies ...
Pétur Björgvin Þorsteinsson +1 more
core
The future work self and calling: The mediational role of life meaning [PDF]
, 2017 Research on calling prevailingly focuses on the positive effects on well-being and career development. However, explorations of the predictors and emergence of callings are sparse.
Zhang, Chunyu +4 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Makna Hidup (Meaning in Life) pada Wanita yang Terdiagnosa Positif HIV di Masa Kehamilan
GuidenaThe Human Immunodeficiency Virus (HIV) is a virus that targets the human immune system. Pregnancy accompanied by HIV carries the risk of transmission from the mother to the infant, both during gestation, during the birthing process, and through ...
Dewa Ayu Venny Ardhana +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source