Results 171 to 180 of about 173,239 (326)

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

The R-process Alliance: Enrichment of r-process Elements in a Simulated Milky Way–like Galaxy

The Astrophysical Journal
We study the formation of stars with varying amounts of heavy elements synthesized by the rapid neutron-capture process ( r -process) based on our detailed cosmological zoom-in simulation of a Milky Way–like galaxy with an N -body/smoothed particle ...
Yutaka Hirai, Timothy C. Beers, Young Sun Lee, Shinya Wanajo, Ian U. Roederer, Masaomi Tanaka, Masashi Chiba, Takayuki R. Saitoh, Vinicius M. Placco, Terese T. Hansen, Rana Ezzeddine, Anna Frebel, Erika M. Holmbeck, Charli M. Sakari   +13 more
doaj   +1 more source

Dust Grain-Size Distributions and Extinction in the Milky Way, Large Magellanic Cloud, and Small Magellanic Cloud

, 2001
J. Weingartner, B. Draine
semanticscholar   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou, Chaoyang Huang, Yanqi Chen, Tingzi Zhao, Fengyi Zhu, Gong Jun, Jinrong Zhang, Yingsong Pan, Qiulan Wen, Lei Yang, Huihui Zhang, Lianglong Chen   +11 more
wiley   +1 more source

The Structural and Kinematical Properties of NGC 5634, a Globular Cluster Associated with the Sagittarius Dwarf Galaxy?

The Astrophysical Journal
We investigate the origin of NGC 5634 through a comprehensive analysis of its morphology, kinematics, and dynamics. Utilizing data from the DESI Legacy Survey, we refined its fundamental parameters (age τ = 12.8 ± 0.3 Gyr, metallicity [Fe/H] = −1.8 ± 0.1
Shouzhi Wang, Jundan Nie, Biwei Jiang, Hao Tian, Chao Liu, Ying-Hua Zhang   +5 more
doaj   +1 more source

Biomimetic Copper Nanoparticles Coated with ACE2‐Overexpressing Membranes for Selective SARS‐CoV‐2 Neutralization and Disinfection

Advanced Healthcare Materials, EarlyView.
By fusing ACE2‐overexpressing membrane‐integrated liposome (MIL) with copper nanoparticles, the biomimetic Cu@MIL nanostructures were created that directly hijack the SARS‐CoV‐2 entry pathway. These particles combine potent virus‐targeting precision with intrinsic antiviral activity, achieving rapid neutralization and disinfection.
Pooja Aich, Wei‐Pang Chung, Wen‐Jyun Wang, Hidenobu Takahashi, Ming‐Shun Hsieh, Ying‐Chen Lin, Oh Seok Kwon, Wei‐Peng Li, Wei‐Lun Huang   +8 more
wiley   +1 more source

Chemo-dynamical Evolution of Simulated Satellites for a Milky Way–like Galaxy

The Astrophysical Journal
The chemical abundances of Milky Way’s (MW's) satellites reflect their star formation histories (SFHs), yet, due to the difficulty of determining the ages of old stars, the SFHs of most satellites are poorly measured.
Yutaka Hirai, Evan N. Kirby, Masashi Chiba, Kohei Hayashi, Borja Anguiano, Takayuki R. Saitoh, Miho N. Ishigaki, Timothy C. Beers   +7 more
doaj   +1 more source

Thermo‐Fluorescent Bactericidal Quantum Dots Based Smart Multifunctional Textiles via Molecular Surface Engineering and 3D‐Printed Interlocked Architectures

Advanced Healthcare Materials, EarlyView.
A versatile approach is presented for fabricating smart multifunctional textiles by integrating thermo‐fluorescent carbon dot/polymer nanocomposite coatings with 3D‐printed interlocked architectures. The fabrics exhibit temperature‐responsive fluorescence, durable hydrophobicity, strong antibacterial and antioxidant activity, and enhanced UV protection.
Poushali Das, Sayan Ganguly, Parham Khoshbakht Marvi, Misha Muthalali, Fatemeh Parniani, Shiza Hassan, Xiaowu (Shirley) Tang, Seshasai Srinivasan, Amin Reza Rajabzadeh   +8 more
wiley   +1 more source

Observational Signatures of AGN Feedback in the Morphology and the Ionization States of Milky Way-like Galaxies

The Astrophysical Journal
We make an in-depth analysis of different active galactic nuclei (AGN) jet models’ signatures, inducing quiescence in galaxies with a halo mass of 10 ^12 M _⊙ .
Nadia Qutob, Razieh Emami, Kung-Yi Su, Randall Smith, Lars Hernquist, Dian P. Triani, Cameron Hummels, Drummond Fielding, Philip F. Hopkins, Rachel S. Somerville, David R. Ballantyne, Mark Vogelsberger, Grant Tremblay, James F. Steiner, Douglas Finkbeiner, Ramesh Narayan, Minjung Park, Josh Grindlay, Priyamvada Natarajan, Christopher C. Hayward, Dušan Kereš, Sam B. Ponnada, Sirio Belli, Rebecca Davies, Gabriel Maheson, Letizia Bugiani, Yijia Li   +26 more
doaj   +1 more source

Zinc‐Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun, XueBo Wei, ZhuoYang Song, JunJun Luo, JingYi Ye, YinNan Zhang, LiFei Zhu, Jie Gao, Hongyu Zhang, Hong Zhu, Xin Wang, Ke Xu   +11 more
wiley   +1 more source