Results 81 to 90 of about 128,506,783 (259)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Reconstructing a Prehistoric Fish Trap

open access: yesEXARC Journal, 2014
Fish traps, still in use all over the world today for catching fish and crustaceans, have been used by mankind at least since the Mesolithic period. Their shape at that time is quite well-established, suggesting that they may have originated even earlier
Eva IJsveld
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

PAN-00000911 - pin of the North Sea coast type

open access: yes, 2018
This find is registered at Portable Antiquities of the Netherlands with number PAN ...
Portable Antiquities of the Netherlands, DataCurator
core   +1 more source

PAN-00010291 - Roman narrow profiled mount of the type Regensburg

open access: yes, 2023
This find is registered at Portable Antiquities of the Netherlands with number PAN ...
Portable Antiquities of the Netherlands, DataCurator
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Should we be Scared of all Salafists in Europe?

open access: yesPerspectives on Terrorism, 2014
European governments consider the Salafi movement to be primarily a security threat. Yet developments in the Dutch Salafi movement reveal that quietist and political Salafists distance themselves from coercion and violence in the European context and ...
Ineke Roex
doaj  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

PAN-00019150 - Roman square belt mount of the Velsen type

open access: yes, 2020
This find is registered at Portable Antiquities of the Netherlands with number PAN ...
Portable Antiquities of the Netherlands, DataCurator
core   +1 more source

INVESTMENT ENVIRONMENT OF THE NETHERLANDS [PDF]

open access: yesÊvropejsʹkij Vektor Ekonomìčnogo Rozvitku
The paper offers a comprehensive review of the investment environment in the Netherlands, a nation noted for its advanced economy, robust international trade links, and a solid legal framework that supports business activity. The Netherlands features a
Viktoriia М. Sbitenkova
doaj   +1 more source

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