Results 91 to 100 of about 1,660 (216)

Model studies toward the total synthesis of thebaine by an intramolecular cycloaddition strategy

open access: yes, 2014
The present studies describe recent progress toward the synthesis of the thebaine. Model substrates were synthesized using pyridazine derivatives as a starting material, which allowed to assess the key Diels-Alder reaction as a route to construct the ...
Gupta, Setu
core  

A study on the mechanism of the interaction between strychnine and thebaine.

open access: yes, 1972
Although strychnine and thebaine have very similar convulsant actions, mixtures of the two drugs were found to interact infra-additively in intact mice.
Laskey, Wendy.
core  

Pharmacological Study of Thebaine Derivative

open access: yesNippon Yakubutsugaku Zasshi (Folia Pharmacologica Japonica), 1937
From its pharmacological action, thebaine, a kind of opium alkaloid, should be classed in the group of spasmodic poisons, but the writer has already reported that when it was changed into oxycodeinone by oxidation and into dehydrooxycodeinone by hydration, spasmodic peripheral action decreased, and instead, a paralysing action of the cerebruur and the ...
openaire   +3 more sources

Alternative methods for the MnO2 oxidation of codeine methyl ether to thebaine utilizing ionic liquids

open access: yes, 2001
The MnO2 oxidation of codeine methyl ether, CME, to thebaine has been accomplished via the use of the ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate, bmimBF4.
R Singer (4048546)   +1 more
core  

Application of Conventional and New Biotechnological Approaches for Improving of Morphinane Alkaloids Production

open access: yesJournal of Medicinal Plants, 2010
More than 12,000 alkaloids are known in plants, mostly used as medicine with a world market value of about 4 billion US$. Opium poppy, Papaver somniferum, is the most important economic source of morphinane alkaloids such as morphine, codeine, thebaine ...
E Dehghan   +3 more
doaj  

In-vitro Characterizing of Thebaine Inhibition on Salutaridinol-7-O-acetyltransferase in Morphine Biosynthesis

open access: yes
Opiates, such as morphine, have been used for medicinal purposes throughout human history. These bioactive compounds are produced in the opium poppy (Papaver somniferum) through complex biosynthetic pathways. This study aimed to characterize the in-vitro
Kapasi, Moiz Shabbir
core   +1 more source

A Simple and Practical Method for the Oxidation of Thebaine to 14-Hydroxycodeinone by V2O5–H2O2 [PDF]

open access: yes, 2009
An efficient, practical and expeditious method has been developed for the oxidation of thebaine to 14-hydroxycodeinone in excellent yield by employing 20 mol% of V2O5 in the presence of 30% H2O2 in aqueous medium.
Konwar, D, Das, Saikat Das
core  

The Estimation of Morphine, Codeine and Thebaine in Opium and in Poppy Latex by Paper Chromatography

open access: yes, 1963
The recommended method involves separation of the morphine from the mixed alkaloids in chloroform using 0·1n sodium hydroxide and separation of the codeine and thebaine by means of a buffer solution of pH 2·0.
Gamila Wassel, J W Fairbairn
core   +1 more source

Review of poppy (Papaver somniferum L.)

open access: yesJournal of Medicinal Plants, 2003
Poppy (Papaver somniferum L.) is a member of the papaveraceae family. It is indigenus of south east of Europe and Asia. It is cultivated in over the world and there is not any wild type of this specie. Until now more than 40 different alkaloids have been
D Yazdani, S Rezazadeh, S Shahnazi
doaj  

Determination of relative response factors of the opium alkaloids with HPLC-DAD [PDF]

open access: yesMakedonsko Farmacevtski Bilten, 2012
In this work, a convenient method for determination of relative UV response factors (RRFs) of morphine, codeine, thebaine, oripavine, noscapine and papaverine by high performance liquid chromatography (HPLC) equipped with a diode array detector (DAD) was
Jelena Acevska   +5 more
doaj  

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