Results 181 to 190 of about 3,011 (215)

Oxonium ion intermediates in the rearrangement of thebaine

Journal of the Chemical Society D: Chemical Communications, 1969
The rearrangement of thebaine and its metho-salts in trifluoroacetic acid has been shown to involve red oxonium ion intermediates. Quaternary salts of 7,8-dehydrometathebainone have been isolated and a convenient preparation of neodihydrothebaine from thebaine has been devised.
G. W. Kirby, R. T. Channon, S. R. Massey
openaire   +3 more sources

Novel analgesics and molecular rearrangements in the morphine–thebaine group. Part XVII. Compounds related to the thebaine–maleic anhydride adduct

J. Chem. Soc. C, 1970
A number of derivatives of the thebaine–maleic anhydride, thebaine–ethyl maleate, and thebaine–N-phenyl-maleimide adducts has been prepared. Some of the derivatives are potent morphine-like drugs.
W. I. Rushworth, J. W. Lewis
openaire   +3 more sources

Selective Olefin Reduction in Thebaine Using Hydrazine Hydrate and O2 under Intensified Continuous Flow Conditions

, 2016
Hydrocodone, a high value active pharmaceutical ingredient (API), is usually produced in a semisynthetic pathway from morphine, codeine or thebaine. The latter alkaloid is an attractive precursor as it is not used as a remedy itself. The key step in this
Bartholomäus Pieber, D. Cox, C. Kappe
semanticscholar   +1 more source

Thebaine induces anaphylactic reactions via the MRGPRX2 receptor pathway on mast cells.

Cellular Immunology, 2022
Pan Lei, Yanhong Liu, Yifan Ding, Xinyue Su, Jinna Liang, Hua Chen, Weina Ma   +6 more
semanticscholar   +1 more source

Production of monoclonal antibodies and ELISA for thebaine and codeine

Cytotechnology, 1996
The ratio of hapten and bovine serum albumin in antigen conjugate was exactly determined by matrix-assisted laser desorption/ionization mass spectrometry. Monoclonal antibodies against thebaine and codeine were produced by hybridoma fused with the sprenocytes immunized with thebaine- and codeine-bovine serum albumin conjugate and HAT-sensitive mouse ...
Yukihiro Shoyama, Tomohiro Fukada, Hiroki Murakami   +2 more
openaire   +3 more sources

Thebaine and acetylenic dienophiles [PDF]

The Journal of Organic Chemistry, 1982
S. Archer, J. Hirshfield, Amrik Singh, Karst Hoogsteen   +3 more
openaire   +1 more source

Direct Synthesis of Noroxymorph­one from Thebaine: Unusual CeIV Oxidation of a Methoxydiene‐Iron Complex to an Enone‐γ‐Nitrate

, 2016
Noroxymorphone was prepared from thebaine in seven operations. The key steps involved the successive N- and O-demethylations of an iron tricarbonyl complex of thebaine followed by the unusual ceric ammonium nitrate oxidation of the methoxydiene moiety to
Aleš Machara, M. Endoma-Arias, I. Císařová, D. Phillip Cox, T. Hudlický   +4 more
semanticscholar   +1 more source

Some notes on the reduction of thebaine and related topics

Experientia, 1950
P. Karrer hat vor kurzem die Darstellung eines neuen Dihydrothebains durch Reduktion der Base mit Lithium-Aluminium-Hydrid beschrieben. Die Autoren konnen die Ergebnisse ihrer eigenen Arbeiten auf diesem Gebiet wie folgt zusammenfassen: Reduktion von Thebain vermittels Natrium in flussigem Ammoniak ergibt eine nahezu quantitative Ausbeute an ...
K. W. Bentley, R. Robinson
openaire   +3 more sources

Über das β‐Dihydro‐thebain

Helvetica Chimica Acta, 1950
AbstractThebain wird durch LiAlH4 in ein Dihydro‐thebain (β‐Dihydrothebain, VI) übergeführt, dessen Konstitution ermittelt worden ist. Die Verbindung ist stereoisomer mit dem schon bekannten „Thebainon‐enol‐methyläther”︁ (V) und unterscheidet sich von diesem durch Konfigurationsänderung am C‐Atom 14.
Hans Schmid, P. Karrer
openaire   +2 more sources

Determination of morphine, codeine, and thebaine concentrations from poppy seed tea using magnetic carbon nanotubes facilitated dispersive micro-solid phase extraction and GC-MS analysis.

Forensic Science International, 2021
S. Li, Madeleine J. Swortwood, J. Yu
semanticscholar   +1 more source