Results 161 to 170 of about 1,660 (216)
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Conversion of thebaine to codeine
Journal of Medicinal Chemistry, 1976An improved conversion of thebaine to codeine has been developed. Oxymercuration of thebaine with mercuric acetate in refluxing methanol, followed by hydrolysis of the intermediate 7-acetomercurineopinone dimethyl ketal with 3 N acetic acid, or, alternatively, reduction of the organomercury compound with sodium borohydride and mild acid hydrolysis of ...
R B, Barber, H, Rapoport
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Spectrofluorimetric determination of thebaine
Mikrochimica Acta, 1975A method has been developed for the determination of morphine hydrochloride, codeine, papaverine, narcotine and thebaine in mixtures, by measurement of the native fluorescence of the first four components, the fluorescence of the apomorphine obtained by oxidation of morphine, and the fluorescence of the hydrolysis products obtained by heating thebaine ...
R A, Chalmers, A F, Jackson
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Thebain?Maleinimid-und Thebain?N-substituierte Maleinimid-Addukte
Monatshefte f�r Chemie, 1971DasDiels-Alder-Addukt Thebain—Maleinimid wurde auf verschiedenen Wegen hergestellt. Substitution am Imidstickstoff durch Alkylhalogenide lieferte die entsprechenden N-Alkylderivate und durch Bromessigsaureathylester die entsprechende N-Carbathoxymethylverbindung. Aminolyse dieses Esters fuhrte zu einer Reihe von Amiden.
O. Hromatka +2 more
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The nitration of thebaine with tetranitromethane
Journal of the Chemical Society, Perkin Transactions 1, 1981Thebaine (1) reacts in methanol with tetranitromethane to give, as the major product, 14β-nitrocodeinone dimethyl acetal (2a), which has been converted into, inter alia, 14β-nitrocodeinone (3a), 14β-aminocodeinone dimethyl acetal (2b), 14β-aminocodeinone (3b), and 14β-aminocodeine.
Robert M. Allen +2 more
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The Analyst, 1984
The determination of the thebaine content of crude thebaine concentrates by infrared and ultraviolet spectrophotometric methods is described. The results obtained with the two methods were found to compare favourably. The accuracy of these procedures was found to be superior to that of the K–34 (U.N.) method.
Arun Agnihotri +4 more
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The determination of the thebaine content of crude thebaine concentrates by infrared and ultraviolet spectrophotometric methods is described. The results obtained with the two methods were found to compare favourably. The accuracy of these procedures was found to be superior to that of the K–34 (U.N.) method.
Arun Agnihotri +4 more
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The pharmacology of thebaine in the chronic spinal dog
Drug and Alcohol Dependence, 1978The effects of thebaine were studied in nondependent and morphine-dependent chronic spinal dogs as well as in chronic spinal dogs receiving thebaine chronically. Thebaine did not produce any morphine-like effects in nondependent dogs nor did it precipitate an abstinence syndrome in morphine-dependent dogs.
P E, Gilbert, W R, Martin
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Thebaine Adducts with Maleimides. Synthesis and Transformations.
ChemInform, 2005AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
E.E. Shults +4 more
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ChemInform Abstract: THEBAINE AND ACETYLENIC DIENOPHILES
Chemischer Informationsdienst, 1982AbstractThebain (1) reagiert mit Propiolsäuremethylester (II) in Methanol zu den beiden Addukten(I1I) und (IV).
A. SINGH +3 more
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Cyclo-adducts of thebaine with nitrosoarenes
Journal of the Chemical Society, Perkin Transactions 1, 1979Thebaine (1) reacts reversibly with various nitroso-arenes to form cyclo-adducts by 1,4-addition of the nitrosogroup to the conjugated diene system of the alkaloid. Adducts (2) of thebaine with nitrosobenzene and with 4-chloro-, 4-methyl-, 3-methoxy-, and 4-nitro-nitrosobenzene have been prepared in good yield.
Gordon W. Kirby +3 more
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Study on Synthesis of Thebaine Derivatives
Chinese Journal of Chemistry, 2005The reaction of 7α-acetyl-6,14-endoethano-6,7,8,14-tetrahydrothebaine with 2-(thien-2-yl)ethylmagnesium bromide was investigated. The tertiary alcohol derivative 7α-[R-1-hydroxyl-1-methyl-3-(thien-2-yl)propyl])-6,14-endoethano-6,7,8,14-tetrahydrothebaine (3) and a by-product 4 were isolated. The structure of 4 was elucidated by X-ray analysis.
He Liu +4 more
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