Results 161 to 170 of about 3,283 (227)

Proteomics: An Essential Tool to Study Plant-Specialized Metabolism. [PDF]

Biomolecules
Martínez-Esteso MJ, Morante-Carriel J, Samper-Herrero A, Martínez-Márquez A, Sellés-Marchart S, Nájera H, Bru-Martínez R.   +6 more
europepmc   +1 more source

Rank annihilation factor analysis for kinetic spectrophotometric determination of morphine in unknown samples. [PDF]

Sci Rep
Bahram M, Khezri S, Dadashi R.
europepmc   +1 more source

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Structural insights into thebaine synthase 2 catalysis

Biochemical and Biophysical Research Communications, 2020
Thebaine synthase 2 (THS2) that can transform (7S)-salutaridinol 7-O-acetate to thebaine catalyzes the final step of thebaine biosynthesis in Papaver somniferum. Here, the crystal structures of THS2 and its complex with thebaine are reported, revealing the interaction network in the substrate-binding pocket.
Chun-Chi Chen, Wei Peng, Binju Wang
exaly   +3 more sources

Thebaine Cyclopropanation.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
E. E. Schultz, M. M. Shakirov, I. Yu. Bagryanskaya, Yu. V. Gatilov, G. A. Tolstikov, V. N. Kalinin, H. Schmidhammer   +6 more
openaire   +1 more source

Dearomative Access to (−)-Thebaine and Derivatives

Organic Letters, 2023
A synthesis of the natural product thebaine is reported in eight steps from commercially available starting materials, hinging on the dearomatization and coupling of simple aromatic starting materials. This provides divergent access to two unnatural opioid derivatives and is aimed at the long-term development of synthetic opioid analogs of the ...
Zachary A. Tolchin, Dallas M. Dukes, Leanna M. Gharbaoui, Joel M. Smith   +3 more
openaire   +2 more sources

Thebain?Maleinimid-und Thebain?N-substituierte Maleinimid-Addukte

Monatshefte f�r Chemie, 1971
DasDiels-Alder-Addukt Thebain—Maleinimid wurde auf verschiedenen Wegen hergestellt. Substitution am Imidstickstoff durch Alkylhalogenide lieferte die entsprechenden N-Alkylderivate und durch Bromessigsaureathylester die entsprechende N-Carbathoxymethylverbindung. Aminolyse dieses Esters fuhrte zu einer Reihe von Amiden.
O. Hromatka, G. Sengstschmid, K. Eichinger   +2 more
openaire   +1 more source

Spectrofluorimetric determination of thebaine

Mikrochimica Acta, 1975
A method has been developed for the determination of morphine hydrochloride, codeine, papaverine, narcotine and thebaine in mixtures, by measurement of the native fluorescence of the first four components, the fluorescence of the apomorphine obtained by oxidation of morphine, and the fluorescence of the hydrolysis products obtained by heating thebaine ...
R A, Chalmers, A F, Jackson
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Conversion of thebaine to codeine

Journal of Medicinal Chemistry, 1976
An improved conversion of thebaine to codeine has been developed. Oxymercuration of thebaine with mercuric acetate in refluxing methanol, followed by hydrolysis of the intermediate 7-acetomercurineopinone dimethyl ketal with 3 N acetic acid, or, alternatively, reduction of the organomercury compound with sodium borohydride and mild acid hydrolysis of ...
R B, Barber, H, Rapoport
openaire   +2 more sources