Results 241 to 250 of about 5,049 (275)

Study on Synthesis of Thebaine Derivatives

Chinese Journal of Chemistry, 2005
The reaction of 7α-acetyl-6,14-endoethano-6,7,8,14-tetrahydrothebaine with 2-(thien-2-yl)ethylmagnesium bromide was investigated. The tertiary alcohol derivative 7α-[R-1-hydroxyl-1-methyl-3-(thien-2-yl)propyl])-6,14-endoethano-6,7,8,14-tetrahydrothebaine (3) and a by-product 4 were isolated. The structure of 4 was elucidated by X-ray analysis.
He Liu, Chun-He Liu, Bo-Hua Zhong, Bo Wu, Ze-Hui Gong   +4 more
openaire   +2 more sources

Reaction of thebaine with dinitrogen tetroxide

Journal of Heterocyclic Chemistry, 1979
AbstractTreatment of thebaine with dinitrogen tetroxide gave a mixture of 14β‐nitrocodeinone (23%) and 8‐nitrothebaine (7%).
Sydney Archer, Peter Osei-Gyimah
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ChemInform Abstract: THEBAINE AND ACETYLENIC DIENOPHILES

Chemischer Informationsdienst, 1982
AbstractThebain (1) reagiert mit Propiolsäuremethylester (II) in Methanol zu den beiden Addukten(I1I) und (IV).
A. SINGH, S. ARCHER, K. HOOGSTEEN, J. HIRSHFIELD   +3 more
openaire   +1 more source

Pharmacokinetics and Metabolism of [³H] Thebaine

Xenobiotica, 1974
1. A method is described for determination of [3H]thebaine in biological materials with sensitivity of 10–20 ng.2. Following a 5 mg/kg subcutaneous dose of [3H]thebaine to rats, max. brain and plasma concns. were 937 ng/g and 1076 ng/ml at 0.5 and 1 h, respectively; these declined to non-detectable levels at 24 h.
R B Pontani, A L Misra, S J Mulé
openaire   +3 more sources

Direct and Simple O-Demethylation of Thebaine to Oripavine

The Journal of Organic Chemistry, 1996
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Coop, A, Lewis, JW, Rice, KC
openaire   +4 more sources

Mikrobielle Umwandlung von Thebain

Experientia, 1969
Thebaine was transformed into 2 products by fermentation with a strain ofTrametes cinnabarina. The 2 compounds were isolated and identified as 14-Β-hydroxycodeinone and 14-Β-hydroxycodeinone-N-oxid.
D. Gröger, H. P. Schmauder
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Acyl‐normethine aus Thebain

Chemische Berichte, 1967
AbstractBei der Öffnung des Piperidinringes im Thebain mit Acetyl‐ und Benzoylchlorid sowie Chlorameisensäure‐äthyl‐und ‐benzylester in feuchtem Äthylacetat entstehen die entsprechen‐den Codeinon‐acyl‐normethine (1a–1d), die je nach Katalyse interessante Umlagerungs‐und Spaltungsreaktionen eingehen.
Christa Bertgen, Franz Vieböck, Wilhelm Fleischhacker   +2 more
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Addition reaction of thebaine and β-dihydrothebaine with phenylsulphonylpropadiene

J. Chem. Soc., Chem. Commun., 1984
AbstractThebain (I) reagiert mit Phenylsulfonylallen (II) zu einem untrennbaren Gemisch der Addukte (IIIa) und (IIIb), die bei der Hydrolyse nur ein Keton (IV) ergeben.
K. Ryu, Ikuo Fujii, K. Hayakawa, K. Kanematsu   +3 more
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Novel analgesics and molecular rearrangements in the morphine–thebaine group. Part XIX. Further Diels–Alder adducts of thebaine

J. Chem. Soc. C, 1971
The reaction of thebaine with a number of 1,1-disubstituted ethylenes has been investigated; structures have been assigned to the adducts formed.
I. A. Selby, M. J. Readhead, J. W. Lewis, A. C. B. Smith, C. A. Young   +4 more
openaire   +3 more sources

Colorimetric Determination of Thebaine in Papauer Bracteatum

Journal of Pharmaceutical Sciences, 1981
A rapid colorimetric test for the determination of thebaine in dried, extracted Papaver bracteatum is described. The method is based on the development of an orange color formed by the nitroso color reaction for phenols. The absorption peak is near 450 nm. The linear range response is from 0 to 1.0 mg of thebaine.
openaire   +3 more sources