In silico identification of Theileria parva surface proteins [PDF]
East Coast Fever is a devastating African cattle disease caused by the apicomplexan parasite, Theileria parva. Little is known about the cell surface, and few proteins have been identified.
Nitisha Gurav +3 more
doaj +6 more sources
Anti-parasitic benzoxaboroles are ineffective against Theileria parva in vitro [PDF]
East Coast Fever (ECF) is a disease affecting cattle in sub-Saharan Africa, caused by the tick-borne Apicomplexan pathogen Theileria parva. The disease is a major problem for cattle farmers in affected regions and there are few methods of control ...
Pieter C. Steketee +5 more
doaj +2 more sources
Theileria parva in Zambia: A scoping review protocol. [PDF]
ObjectiveThe objective of this scoping review is to examine published and unpublished literature on Theileria parva in Zambia. It will identify the scope of available literature for research prioritization.IntroductionTheileria parva is the most lethal ...
Chishimba M Mubanga +3 more
doaj +2 more sources
Comparative transcriptional analysis identifies genes associated with the attenuation of Theileria parva infected cells after long-term in vitro culture [PDF]
Autologous administration of attenuated Theileria parva-infected cells induces immunity to T. parva in cattle. The mechanism of attenuation, however, is largely unknown. Here, we used RNA sequencing of pathogenic and attenuated T.
Elisabeth M. D. L. van der Heijden +5 more
doaj +2 more sources
Unique Mitochondrial Single Nucleotide Polymorphisms Demonstrate Resolution Potential to Discriminate Theileria parva Vaccine and Buffalo-Derived Strains [PDF]
Distinct pathogenic and epidemiological features underlie different Theileria parva strains resulting in different clinical manifestations of East Coast Fever and Corridor Disease in susceptible cattle.
Micky M. Mwamuye +6 more
doaj +2 more sources
An Improved Theileria parva Sporozoite Seroneutralization Assay for the Identification of East Coast Fever Immune Correlates [PDF]
Background: Immune correlates of protection are ideal tools to predict treatment or vaccine efficacy. However, the accuracy of the immune correlate and the capability to robustly predict the outcome of a vaccine candidate are determined by the ...
Hannah Chege +10 more
doaj +2 more sources
Characterization of the Theileria parva sporozoite proteome. [PDF]
East Coast fever is a lymphoproliferative disease caused by the tick-borne protozoan parasite Theileria parva. The sporozoite stage of this parasite, harboured and released from the salivary glands of the tick Rhipicephalus appendiculatus during feeding, invades and establishes infection in bovine lymphocytes.
Nyagwange J +7 more
europepmc +4 more sources
Morbidity, mortality, and risk factors associated with Theileria parva seropositivity in a longitudinal calf study, Narok, Kenya [PDF]
East Coast fever (ECF), caused by Theileria parva causes devastating loss to livestock keepers in sub-Saharan Africa. A longitudinal study was carried out in Narok County to estimate the incidence and risk factors associated with Theileria parva ...
Wyckliff Ngetich +4 more
doaj +2 more sources
South African Buffalo-Derived Theileria parva Is Distinct From Other Buffalo and Cattle-Derived T. parva [PDF]
Theileria parva is a protozoan parasite transmitted by the brown-eared ticks, Rhipicephalus appendiculatus and Rhipicephalus zambeziensis. Buffaloes are the parasite’s ancestral host, with cattle being the most recent host.
Boitumelo B. Maboko +12 more
doaj +2 more sources
Antigenic Diversity in Theileria parva Populations From Sympatric Cattle and African Buffalo Analyzed Using Long Read Sequencing [PDF]
East Coast fever (ECF) in cattle is caused by the Apicomplexan protozoan parasite Theileria parva, transmitted by the three-host tick Rhipicephalus appendiculatus. The African buffalo (Syncerus caffer) is the natural host for T. parva but does not suffer
Fiona K. Allan +15 more
doaj +2 more sources

