Results 1 to 10 of about 63,352 (254)
Isolation, characterization and application of theophylline-degrading Aspergillus fungi
Microbial Cell Factories, 2020 Background Caffeine, theobromine and theophylline are main purine alkaloid in tea. Theophylline is the downstream metabolite and it remains at a very low level in Camellia sinensis.
Binxing Zhou +6 more
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Molecular simulations and Markov state modeling reveal the structural diversity and dynamics of a theophylline-binding RNA aptamer in its unbound state. [PDF]
PLoS ONE, 2017 RNA aptamers are oligonucleotides that bind with high specificity and affinity to target ligands. In the absence of bound ligand, secondary structures of RNA aptamers are generally stable, but single-stranded and loop regions, including ligand binding ...
Becka M Warfield, Peter C Anderson
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Pharmaceuticals, 2010 Theophylline (3-methyxanthine) has been used to treat airway diseases for over 70 years. It was originally used as a bronchodilator but the relatively high doses required are associated with frequent side effects, so its use declined as inhaled β2 ...
Peter J. Barnes
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PLoS ONE, 2021 BackgroundA synergism has been reported between theophylline and corticosteroids, wherein theophylline increases and restores the anti-inflammatory effect of inhaled corticosteroids (ICS) by enhancing histone deacetylase-2 (HDAC) activity.
Tiankui Shuai +6 more
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The Impact of CYP1A2 and CYP2E1 Genes Polymorphism on Theophylline Response [PDF]
Journal of Clinical and Diagnostic Research, 2016 Theophylline is a medicine with narrow therapeutic index. This implies that a small change in dosage would cause side effects. Theophylline is metabolized by CYP1A2 and CYP2E1.
Em Sutrisna
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Electroanalytical overview: The electroanalytical detection of theophylline
Talanta Open, 2021 In this overview, we explore the electroanalytical determination of theophylline. Theophylline finds use as a bronchodilator for treating diseases such as asthma and chronic obstructive pulmonary disease (COPD).
Robert D. Crapnell, Craig E. Banks
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A Prospective Survey on Safety of Sustained-Release Theophylline in Treatment of Asthma and COPD
Allergology International, 2006 Background: Theophylline is a useful drug for the treatment of asthma. The Asthma Prevention and Management Guidelines (JGL) recommend use of sustained-release theophylline products as controllers and of injectable aminophylline products as relievers ...
Sohei Makino +7 more
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Prophylactic Theophyline reduces birth asphyxia related renal injury in term neonates
Journal of Rawalpindi Medical College, 2023 BACKGROUND INTRODUCTION: Birth Asphyxia (Perinatal Asphyxia) in newborn is a condition caused by the inadequate supply of oxygen before, during, or just after birth. Kidney is the most damaged organ in asphyxiated full-term infants.
Salma Aziz +5 more
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Prospective Survey on Safety Evaluation of Injectable Methylxanthines in Japan
Allergology International, 2006 Background: Injectable methylxanthines are useful drugs in the treatment of asthma. The Asthma Prevention and Management Guidelines (JGL) that are followed in Japan recommend the use of sustained-release theophylline to control the disease and use of ...
Ken Ohta +7 more
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Journal of Pharmacological Sciences, 2008 Although theophylline has been suggested to have an anti-inflammatory effect, there have been few reports to show the in vivo effect and the mechanism of anti-inflammatory activity of theophylline experimentally.
Shigekazu Watanabe +5 more
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