Pharmaceuticals, 2010 Theophylline (3-methyxanthine) has been used to treat airway diseases for over 70 years. It was originally used as a bronchodilator but the relatively high doses required are associated with frequent side effects, so its use declined as inhaled β2 ...
Peter J. Barnes
doaj +8 more sources
Pharmacodynamic and pharmacokinetic effects of flumazenil and theophylline application in rats acutely intoxicated by diazepam [PDF]
Vojnosanitetski Pregled, 2009 Background/Aim. The majority of symptoms and signs of acute diazepam poisoning are the consequence of its sedative effect on the CNS affecting selectively polisynaptic routes by stimulating inhibitory action of GABA.
Šegrt Zoran +7 more
doaj +3 more sources
Pulmonary outcomes following specialized respiratory management for acute cervical spinal cord injury: a retrospective analysis. [PDF]
, 2017 Study designRetrospective analysis.ObjectivesTo identify multivariate interactions of respiratory function that are sensitive to spinal cord injury level and pharmacological treatment to promote strategies that increase successful liberation from ...
Crew, JD +5 more
core +1 more source
Prospective Survey on Safety Evaluation of Injectable Methylxanthines in Japan
Allergology International, 2006 Background: Injectable methylxanthines are useful drugs in the treatment of asthma. The Asthma Prevention and Management Guidelines (JGL) that are followed in Japan recommend the use of sustained-release theophylline to control the disease and use of ...
Ken Ohta +7 more
doaj +1 more source
Journal of Pharmacological Sciences, 2008 Although theophylline has been suggested to have an anti-inflammatory effect, there have been few reports to show the in vivo effect and the mechanism of anti-inflammatory activity of theophylline experimentally.
Shigekazu Watanabe +5 more
doaj +1 more source
Tribo-electrification and Powder Adhesion Studies in the Development of Polymeric Hydrophilic Drug Matrices [PDF]
, 2015 The generation of tribo-electric charge during pharmaceutical powder processing can cause a range of complications, including segregation of components leading to content uniformity and particle surface adhesion.
Barbara Conway +7 more
core +2 more sources
Systematic Comparison and Rational Design of Theophylline Riboswitches for Effective Gene Repression
Microbiology Spectrum, 2023 Riboswitches are promising regulatory tools in synthetic biology. To date, 25 theophylline riboswitches have been developed for regulation of gene expression in bacteria. However, no one has systematically evaluated their regulatory effects.
Xun Wang +7 more
doaj +1 more source
Use of low-dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease: study protocol for a randomised controlled trial. [PDF]
, 2015 BACKGROUND: Chronic obstructive pulmonary disease (COPD) is associated with high morbidity, mortality, and health-care costs. An incomplete response to the anti-inflammatory effects of inhaled corticosteroids is present in COPD.
Alyn Morice +68 more
core +4 more sources
Theophylline Enhances In Vitro Fertilization and Embryo Production in Buffaloes
Tropical Animal Science Journal, 2023 This study aimed to investigate the effect of theophylline on in vitro fertilization of buffalo oocytes and embryo development in subsequent in vitro embryo culture.
I. Akter +5 more
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Severe theophylline poisoning treated with continuous venovenous hemodialysis in a child
The Turkish Journal of Pediatrics, 2016 Theophylline poisoning generally occurs due to acute high dose intake as well as chronic intake of the medication. Toxicity symptoms can be seen with a plasma concentration of theophylline over 20 μg/ml.
Ayhan Yaman +7 more
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