Results 31 to 40 of about 85,619 (248)

Effects of process variables on micromeritic properties and drug release of non-degradable microparticles [PDF]

, 2011
Introduction: The purpose of this investigation was to evaluate microencapsulated controlled release preparation of theophylline using Eudragit RS 100 as the retardant material with high entrapment efficiency.
Barar, Jaleh, Jelvehgari, Mitra, Nokhodchi, Ali, Shadrou, Sanam, Valizadeh, Hadi   +4 more
core   +3 more sources

EDTA salt modified carbon paste electrode for square wave voltammetric determination of theophylline in pharmaceutical tablet formulation

PLoS ONE, 2022
In this study, a square wave voltammetric method for determination of theophylline in tablet formulation based on EDTA salt modified carbon paste electrode is presented. CV, FT-IR, and EIS results confirmed modification of the carbon paste with EDTA salt.
Amsalu Moges, Mulugeta Dawit, Mahilet Turbale, Meareg Amare   +3 more
doaj   +2 more sources

Efficacy and safety profile of doxofylline compared to theophylline in asthma: a meta-analysis

Multidisciplinary Respiratory Medicine, 2019
Background Oral methylxanthines are effective drugs for the treatment of chronic obstructive respiratory disorders. The novel methylxanthine doxofylline, that has bronchodilator and anti-inflammatory activities, is not affected by the major drawback of ...
Paola Rogliani, Luigino Calzetta, Josuel Ora, Mario Cazzola, Maria Gabriella Matera   +4 more
doaj   +1 more source

Loss of PopZ At activity in Agrobacterium tumefaciens by Deletion or Depletion Leads to Multiple Growth Poles, Minicells, and Growth Defects. [PDF]

, 2017
Agrobacterium tumefaciens grows by addition of peptidoglycan (PG) at one pole of the bacterium. During the cell cycle, the cell needs to maintain two different developmental programs, one at the growth pole and another at the inert old pole.
Bonnie Bassler, John Zupan, Patricia C. Zambryski, Romain Grangeon, Yeonji Jeon   +4 more
core   +2 more sources

Theophylline exhibits anti-cancer activity via suppressing SRSF3 in cervical and breast cancer cell lines

OncoTarget, 2017
Caffeine, theophylline, and theobromine are the most well-known members of methylxanthines. Caffeine-induced serine/arginine-rich splicing factor 2, SRSF2, and SRSF3 are required for the alternative splicing of a subset of cancer-associated genes ...
Yung-Lung Chang, Y. Hsu, Ying Chen, Yi-Wen Wang, Shih-Ming Huang   +4 more
semanticscholar   +1 more source

Real-time assessment of critical quality attributes of a continuous granulation process [PDF]

, 2013
There exists the intention to shift pharmaceutical manufacturing of solid dosage forms from traditional batch production towards continuous production. The currently applied conventional quality control systems, based on sampling and time-consuming off ...
Córdoba Díaz, Damián, De Beer, Thomas, Fonteyne, Margot, Gildemyn, Delphine, Remon, Jean Paul, Vercruysse, Jurgen, Vervaet, Chris   +6 more
core   +1 more source

Magnetic Solid-phase Extraction with Fe3O4/Molecularly Imprinted Polymers Modified by Deep Eutectic Solvents and Ionic Liquids for the Rapid Purification of Alkaloid Isomers (Theobromine and Theophylline) from Green Tea

Molecules, 2017
Different kinds of deep eutectic solvents (DES) based on choline chloride (ChCl) and ionic liquids (ILs) based on 1-methylimidazole were used to modify Fe3O4/molecularly imprinted polymers (Fe3O4/MIPs), and the resulting materials were applied for the ...
Guizhen Li, Xiaoqin Wang, K. Row
semanticscholar   +1 more source

Calculation of absolute free energy of binding for theophylline and its analogs to RNA aptamer using nonequilibrium work values

, 2007
The massively parallel computation of absolute binding free energy with a well-equilibrated system (MP-CAFEE) has been developed [H. Fujitani, Y. Tanida, M. Ito, G. Jayachandran, C. D. Snow, M. R. Shirts, E. J. Sorin, and V. S. Pande, J. Chem.
Baker, Bayly, Bennett, Berendsen, Boresch, Bustamante, Caldwell, Clore, Collin, Crooks, Crooks, Dang, Essmann, Fujitani, Gilson, Gouda, Hamelberg, Hendrix, Hermans, Hess, Hideaki Fujitani, Hoover, Jakalian, Jarzynski, Jarzynski, Jayachandran, Jenison, Jorgensen, Jorgensen, Kirkwood, Kofke, Kumar, Lindahl, Liphardt, Mahoney, Masakatsu Ito, Massoval, Mobley, Nose, Perlman, Perlman, Ritort, Shirts, Shirts, Sorin, Straatsma, Tembe, Wang, Wang, Wong, Yoshiaki Tanida, Zimmermann, Zwanzig, Åqvist   +53 more
core   +1 more source

A new insight into the oxidative mechanism of caffeine and related methylxanthines in aprotic medium: May caffeine be really considered as an antioxidant? [PDF]

, 2018
Background: Antioxidant properties have been recently suggested for caffeine that seems showing protective effects against damages caused by oxidative stress. In particular, a HO% scavenging activity has been ascribed to caffeine. Even if the oxidation
Curulli, Antonella, Marrosu, Giancarlo, Petrucci, Rita, Zollo, Giuseppe   +3 more
core   +1 more source

Application of a Physiologically Based Pharmacokinetic Model to Study Theophylline Metabolism and Its Interactions With Ciprofloxacin and Caffeine

CPT: Pharmacometrics & Systems Pharmacology, 2016
Theophylline is a commonly used bronchodilator. However, due to its narrow therapeutic range, moderate elevation of serum concentration can result in adverse drug reactions (ADRs).
A Navid, DM Ng, SE Wong, FC Lightstone
doaj   +1 more source