Results 81 to 90 of about 4,204,940 (272)

Modeling and Experimental Analysis of Bias Voltage Effects on Hardness and Thickness of TiN Coatings Produced by PVD Process

open access: yesSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi
This study examines the impact of bias voltage on the mechanical properties and film thickness of TiN coatings deposited on cold work tool steel via the PVD process.
Ahmet Uğur Kaya
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Modeling the History of Astronomy: Ptolemy, Copernicus and Tycho

open access: yes, 2013
This paper describes a series of activities in which students investigate and use the Ptolemaic, Copernican, and Tychonic models of planetary motion. The activities guide students through using open source software to discover important observational ...
Timberlake, Todd
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Financial correlations at ultra-high frequency: theoretical models and empirical estimation

open access: yes, 2011
A detailed analysis of correlation between stock returns at high frequency is compared with simple models of random walks. We focus in particular on the dependence of correlations on time scales - the so-called Epps effect.
A. Lo   +24 more
core   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Computational studies of biomembrane systems: Theoretical considerations, simulation models, and applications

open access: yes, 2013
This chapter summarizes several approaches combining theory, simulation and experiment that aim for a better understanding of phenomena in lipid bilayers and membrane protein systems, covering topics such as lipid rafts, membrane mediated interactions ...
Deserno, Markus   +4 more
core   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Acceptance and use of health information technology in Slovenian public health institutions: a national survey based on UTAUT model

open access: yesZdravniški Vestnik, 2013
Introduction: The purpose of this study was to assess the use and acceptance of information technology (IT) in Slovenian public healthcare institutions.
Matej Vinko   +3 more
doaj  

Collapse models: from theoretical foundations to experimental verifications

open access: yes, 2014
The basic strategy underlying models of spontaneous wave function collapse (collapse models) is to modify the Schroedinger equation by including nonlinear stochastic terms, which tend to localize wave functions in space in a dynamical manner. These terms
Bassi, A., Ulbricht, H.
core   +1 more source

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