Results 51 to 60 of about 3,081,919 (357)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Revista de Estudios Kantianos, 2023 This article attempts to show that the doctrine of the impossibility of total error (DIET) is one of the main presuppositions of Kant's moral thought and not just of his theoretical thought.
Lara Scaglia
doaj +1 more source
General linguistics and Indo-European reconstruction [PDF]
, 2010 There is good reason to be ambivalent about the usefulness of general considerations in linguistic reconstruction. As a heuristic device, a theoretical framework can certainly be helpful, but the negative potential of aprioristic considerations must not ...
Kortlandt, Frederik H. H.
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
On the morals-centeredness of Kant’s transcendental anthropology and on the role of morals in the human nature [PDF]
Кантовский сборник, 2010 This article proves that the philosophical system of Kant is a system of transcendental anthropology, which acts a method in Kant’s pragmatic anthropology. The essence of transcendental anthropology is the metaphysics of morals.
Kalinnikov L. A.
doaj +1 more source
Theoretical Reasons for Economic Sociology [PDF]
SocioEconomic Challenges, 2017 In this paper I try to justify necessity of developing economic sociology in social sciences. In doing so, I present economic sociology as a sub-discipline. The text draws on the interdisciplinary strengths of economic sociology. The core of the article are arguments why economic sociology may be helpful to understand economic life in better way than ...
openaire +2 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Deduction of Freedom vs Deduction of Experience in Kant’s Metaphysics
Кантовский сборник, 2019 My aim is to demonstrate the specificities and differences between transcendental deduction of concepts and deduction of the fundamental principles of pure practical reason in Kant’s metaphysics.
Semyonov V.E
doaj +1 more source
On the moralcentrism of Kant's transcendental anthropology and the role of morals in human nature (continuation) [PDF]
Кантовский сборник, 2011 This article proves that Kant's philosophical system is a system of transcendental anthropology, which acts as a method in Kant’s pragmatic anthropology. The essence of transcendental anthropology is the metaphysics of morals.
Kalinnikov L. A.
doaj +1 more source
The True Destination of EGO is Multi-local Optimization
, 2017 Efficient global optimization is a popular algorithm for the optimization of expensive multimodal black-box functions. One important reason for its popularity is its theoretical foundation of global convergence.
Preuss, Mike, Wessing, Simon
core +1 more source