Results 51 to 60 of about 354,068 (263)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Education SciencesThe development of artificial intelligence (AI) has had a significant impact on various sectors, including education. The successful integration of AI tools in classrooms depends largely on teachers’ understanding and knowledge, confidence, and training.
Zoi A. Traga Philippakos, Louis Rocconi
doaj +1 more source
Theory and Practice of Modern Domestic Preschool Education
Психологическая наука и образование, 2015 The author marked the most important theoretical principles of cultural-historical psychology and activity approach, which underlie the educational standard.
Burlakova I. A.
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Generative AI for Culturally Responsive Science Assessment: A Conceptual Framework
Education SciencesIn diverse classrooms, one of the challenges educators face is creating assessments that reflect the different cultural backgrounds of every student.
Matthew Nyaaba +2 more
doaj +1 more source
Theory and practice of family education in Germany [PDF]
Sociální PedagogikaFamily education is a dynamic academic field in Germany designed to meet parents' needs. The article aims to present the theory and practice of the field, which lies at the intersection of social education and lifelong adult learning.
Kateřina Neubauerová
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Theory and practice of modular education in Russian education
Perspectives of science and EducationIntroduction. Over the past six decades, modular education has been an important didactic approach in modern international and domestic education, and is one of the factors of its development. The purpose of the article is to characterize this important scientific phenomenon, which has a significant impact on the nature and quality of general and ...
Pomelov, Vladimir B. +2 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Africentric Education Leadership: Theory and Practice
International Journal of Education Policy and Leadership, 2008 This article unveils the largely unknown theories and practices of “cultural reattachment Africentric education leaders,” because many people of African descent are now choosing to reattach (in whole or in part) to aspects of certain African cultures (such as Wolof or Akan). The article offers a brief background of African-centered education, discusses
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source