Results 71 to 80 of about 2,701,719 (387)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Theory and practice of modeling gerontological education

SHS Web of Conferences, 2016
On the basis of the basic principles of andragogy and famous models of education A model of education space on the basis of the basic principles of andragogy and famous models of education, created on the basis of a non-state University to persons of the
Lomakina Tatiana Y.
doaj   +1 more source

The Role of Visual Feedback on Power Output During Intermittent Wingate Testing in Ice Hockey Players

Sports, 2018
Background: Visual feedback may help elicit peak performance during different types of strength and power testing, but its effect during the anaerobic Wingate test is unexplored.
Petr Stastny, James J. Tufano, Jan Kregl, Miroslav Petr, Dusan Blazek, Michal Steffl, Robert Roczniok, Milos Fiala, Artur Golas, Piotr Zmijewski   +9 more
doaj   +1 more source

Educational progressivism: Theory and practice

Zbornik Instituta za pedagoska istrazivanja, 2009
The theory and main characteristics of progressivism are studied in the paper. The starting point for research of progressive education is the analysis of its philosophical, psychological and ideological foundations. Numerous aspects of progressivism are discussed in that context: goals of education and learning, role of school, nature of knowledge and
openaire   +3 more sources

The theory–practice nexus in teacher education: new evidence for effective approaches

Journal of Education and Teaching, 2019
All but one of the substantive papers in this issue report on novel approaches to that fundamental issue in teacher education: the relationship between educational theory and the practice of teaching and learning.
Linda la Velle
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Theory and Practice of Modern Domestic Preschool Education

Психологическая наука и образование, 2015
The author marked the most important theoretical principles of cultural-historical psychology and activity approach, which underlie the educational standard.
Burlakova I. A.
doaj   +1 more source

Building professional qualifications as a model of integration and transfer of knowledge [PDF]

, 2013
The multi-faceted nature of transformations that occur in modern business encourages the evolution of concepts, methods and tools of competitiveness, as a result of which, dynamic changes are seen in the theory and practice of management.
Kozielski, Robert
core  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Theory and practice of family education in Germany [PDF]

Sociální Pedagogika
Family education is a dynamic academic field in Germany designed to meet parents' needs. The article aims to present the theory and practice of the field, which lies at the intersection of social education and lifelong adult learning.
Kateřina Neubauerová
doaj   +1 more source