Results 101 to 110 of about 152,877 (259)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Le transmédia comme remédiation de la théorie du récit
Terminal, 2013 Olivier Aïm croise ici une réflexion sur le transmédia storytelling avec une réflexion sur la théorie des idées. Sa démarche s'inscrit dans une étude épistémologique de l'évolution des médias et des métiers médiatiques qui en découlent.
Olivier Aïm
doaj +1 more source
iScienceEven though the Theory of Mind in upper primates has been under investigation for decades, how it may evolve remains an open problem. We propose here an evolutionary game theoretical model where a finite population of individuals may use reasoning strategies to infer a response to the anticipated behavior of others within the context of a sequential ...
Tom Lenaerts +3 more
openaire +5 more sources
Comparative industrial evolution and the quest for an evolutionary theory of market dynamics [PDF]
, 2006 The paper makes the case for an empirically grounded, bottom-up approach to theory building in evolutionary industrial economics. This approach is based on studying systematically selected industries that are comparable in key dimensions.
Buenstorf, Guido
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
La théorie des lieux centraux et les phénomènes d’évolution
Cybergeo, 1999 The evolution of the urban systems goes through different stages. The first is the formation of the whole system where the conformity to the rank-size rule is improving. The second is the transition from the quasi-amorphous state to the quasi-crystalline
Viatcheslav Shuper
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Mechanothermodynamics (on the United Great Competitors: 1850-2015)
Механика машин, механизмов и материалов, 2016 More than 150 years in the framework of mechanics and thermodynamics developed the theory of evolution in the world. The theory of evolution, built in thermodynamics, was, according to modern concepts, unsatisfactory: it predicts the impending heat death
Leonid A. Sosnovskiy
doaj