Results 81 to 90 of about 152,877 (259)

The Taming of Evolution

, 2018
The theory of evolution has clearly altered our views of the biological world, but in the study of human beings, evolutionary and preevolutionary views continue to coexist in a state of perpetual tension.
Greenwood, Davydd
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Evolution of Helping and Harming in Viscous Populations When Group Size Varies

, 2013
Funding: Balliol College and the Royal Society.Recent years have seen huge interest in understanding how demographic factors mediate the evolution of social behavior in viscous populations.
Rodrigues, Antonio M. M., Gardner, Andy
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Hayek’s theory of social evolution in the light of Darwin’s Descent of Man [PDF]

This article proposes to reassess Hayek’s theory of cultural evolution in the light of Darwin’s Descent of Man. It is shown that Hayek and Darwin refers to the same theory of human nature which is borrowed from the founding fathers of political economy ...
Alain Marciano
core  

The Theory of Evolution is Not an Explanation for the Origin of Life

, 2010
The propagation of misconceptions about the theory of biological evolution must be addressed whenever and wherever they are encountered. The recent article by Paz-y-Mino and Espinoza in this journal contained several such misconceptions, including: that ...
Clint D. Kelly, Warner, Daniel, Clough, Michael, Justin W. Rice, Michael P. Clough, Colbert, James, James T. Colbert, Rice, Justin, Kelly, Clint, Daniel A. Warner   +9 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Towards modeling of epigenetic evolution with the aid of theory of open quantum systems

, 2012
We apply theory of open quantum systems to modeling of epigenetic evolution. This is an attempt to unify Darwinian and Lamarckian viewpoints on evolution on the basis of a quantum-like model.
Irina Basieva, Basieva, Irina,, Asano, Masanari,, Yoshiharu Tanaka, Andrei Khrennikov, Tanaka, Yoshiharu,, Yamato, Ichiro,, Masanari Asano, Masanori Ohya, Ichiro Yamato, Ohyna, Masanori,, Khrennikov, Andrei,   +11 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source