Results 91 to 100 of about 152,877 (259)
Behavioural evolution: Darwin's theory and adaptive behaviour
, 2016 When thinking about Darwin's theory of evolution amazing physical adaptations to the challenges of survival come to mind. But it's not just the body that has evolved to fit, behaviour and cognitive abilities are as essential to survival as bones ...
Osthaus, B., Hocking, I.
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Hayek's Theory of Cultural Evolution Revisited: Rules, Morality, and the Sensory Order [PDF]
One of the most controversial parts of F. A. Hayek's work is his theory of cultural evolution. By starting with current discussions on biological and cultural selection theories we bring individual, kin and group selection aspects together and shed some ...
Evelyn Gick, Wolfgang Gick
core
A complex systems perspective on language evolution
Language is acknowledged as a complex adaptive system, but its implications from a modelingperspective remain largely under-explored. This paper explores the application of complex systems theory, as formalized by Thurner, Hanel, and Klimek in their book,
Michaud, Jérôme, Michaud, Jérôme,
core +1 more source
Evolution of Music by Public Choice
, 2012 Music evolves as composers, performers, and consumers favor some musical variants over others. To investigate the role of consumer selection, we constructed a Darwinian music engine consisting of a population of short audio loops that sexually reproduce ...
Burt, A +3 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Sustainability of Human Ecological Niche Construction
Ecology and Society, 2014 Humans influence and depend on natural systems worldwide, creating complex societal-ecological feedbacks that make it difficult to assess the long-term sustainability of contemporary human activities.
Forest Isbell, Michel Loreau
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source