The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
ON THE CREATION OF A RESEARCH COMPETENCIES DEVELOPMENT MODEL FOR HIGHER EDUCATION PROGRAMS GRADUATES
The article addresses one of the most urgent issues of the development of higher education in the light of the challenges of the strategy of scientific and technological development of the Russian Federation and the National system of qualifications ...
E. V. Karavaeva +2 more
doaj
Čtyři empirické principy Ehrenfrieda Walthera von Tschirnhause
This historically oriented study is dedicated to the German naturalist, mathematician and philosopher Ehrenfried Walther von Tschirnhaus (1651–1708) and aims to introduce his main philosophical-logical work, Medicina mentis. After a biographical overview,
Vrtílka, Pavel
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Mapping The Understanding Complex in Russell's Theory of Knowledge [PDF]
Anyone familiar with Russell’s work on the multiple-relation theory of judgment will at some point have puzzled over the map of the five-term understanding complex at the end of Chapter 1, Part II of his Theory of Knowledge (
Perovic, Katarina
core
An Application of Answer Set Programming to the Field of Second Language Acquisition
This paper explores the contributions of Answer Set Programming (ASP) to the study of an established theory from the field of Second Language Acquisition: Input Processing. The theory describes default strategies that learners of a second language use in
Inclezan, Daniela
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
MOLYNEUX'S QUESTION AS ONE OF THE PROBLEMS OF THEORY OF PERCEPTION
The paper contains analysis of Molyneux's question, one of the greatest problems of theory of perception. The problem can be put as, “Could a man born blind and once given the ability to see recognize how things known to him by touch look like?” The ...
A. I. Ponomarev
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Review of Ulrich Baltzer, "Erkenntnis als Relationengeflecht: Kategorien bei Charles S. Peirce" [PDF]
This book arose from the author’s recent dissertation written under the Gerhard Schonrich at Munich. It focuses on Peirce’s theory of categories and his epistemology. According to Baltzer, what is distinctive in Peirce’s theory of knowledge
Callaway, H. G.
core
The Ontology of Knowledge, logic, arithmetic, sets theory and geometry (issue 20210304) [PDF]
In Issue 20210304 the paragraph "intuition of space" is reworded/improved. At ordinary scales, the ontological model proposed by Ontology of Knowledge (OK) does not call into question the representation of the world elaborated by common sense ...
Boucon, Jean-Louis
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source

