Results 91 to 100 of about 5,901,541 (330)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Digital Literacy and Self-Rated Health in China: Dual Pathways Through Information Accessibility and Mental Health

Risk Management and Healthcare Policy
Chunyun Tan,1 Jiangwei Hu,1 Hongxuan Tong,2 Jiale Zhang2,3 1School of Chinese Literature and Media, Hubei University of Arts and Science, Xiangyang, Hubei, People’s Republic of China; 2Institute of Basic Theory for Chinese Medicine, China Academy of ...
Tan C, Hu J, Tong H, Zhang J
doaj  

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Sartre's Theory of Literature

, 1979
As an imaginative writer Sartre is fascinated by the role of imagination in the creative process. Moreover his critical, psychological and philosophical writings witness to a constant meditation on the function and status of the imaginary. This book, originally published in paperback in 1979 under the ISBN 978-0-900547-57-7, was made Open Access in ...
openaire   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Casimir effect from a scattering approach

, 2014
The Casimir force is a spectacular consequence of the existence of vacuum fluctuations and thus deserves a place in courses on quantum theory. We argue that the scattering approach within a one-dimensional field theory is well suited to discuss the ...
Ingold, Gert-Ludwig, Lambrecht, Astrid
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Vacuum Stability of the $\mathcal{PT}$-Symmetric $\left( -\phi^{4}\right) $ Scalar Field Theory

, 2014
In this work, we study the vacuum stability of the classical unstable $\left( -\phi^{4}\right) $ scalar field potential. Regarding this, we obtained the effective potential, up to second order in the coupling, for the theory in $1+1$ and $2+1$ space-time
ABOUZEID M. SHALABY, Peskin M. E.
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source