Results 41 to 50 of about 131,631 (317)

Architectural Principles for Characterizing the Performance of Antithetic Integral Feedback Networks

open access: yesiScience, 2019
Summary: As we begin to design increasingly complex synthetic biomolecular systems, it is essential to develop rational design methodologies that yield predictable circuit performance.
Noah Olsman   +2 more
doaj   +1 more source

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi   +7 more
wiley   +1 more source

Safety management theory and the military expeditionary organization: A critical theoretical reflection [PDF]

open access: yes, 2014
Management of safety within organizations has become a key topic within safety science. Theorizing on this subject covers a diverse pallet of concepts such as “resilience” and “safety management systems”.
Moorkamp, Matthijs   +3 more
core   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

Laplace-Stieltjes transform of the system mean lifetime via geometric process model

open access: yesOpen Mathematics, 2016
Operation principle of the engineering systems occupies an important role in the reliability theory. In most of the studies, the reliability function of the system is obtained analytically according to the structure of the system.
Gökdere Gökhan, Gürcan Mehmet
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Qualitative Reasoning Methodology for the Generation of Process Plant Operating Procedures [PDF]

open access: yes, 1995
The analysis of operating procedures in the early stages of design can lead to safer and higher performance plants. Qualitative reasoning techniques hold considerable promise in supporting generations of operating procedures, since they are able to ...
Vianna, Regina Ferreira
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A Dynamic Analysis of Angular Contact Ball Bearing 7205C Used for a Scraper Conveyor

open access: yesApplied Sciences
As core pieces of transport equipment in longwall mining systems, scraper conveyors operate under extremely harsh and dynamic loading conditions. Their operational reliability and service life primarily depend on the performance of critical components ...
Shaoping Hu   +4 more
doaj   +1 more source

Towards Unification of General Relativity and Quantum Theory: Dendrogram Representation of the Event-Universe

open access: yesEntropy, 2022
Following Smolin, we proceed to unification of general relativity and quantum theory by operating solely with events, i.e., without appealing to physical systems and space-time.
Oded Shor   +2 more
doaj   +1 more source

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