Results 51 to 60 of about 131,631 (317)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Interacting random-field dipole defect model for heating in semiconductor-based qubit devices

Physical Review Research
Semiconductor qubit devices suffer from the drift of important device parameters as they are operated. The most important example is a shift in qubit operating frequencies.
Yujun Choi, Robert Joynt
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Mathematical theory of multiprocessor control systems and its applications [PDF]

Computer Science Journal of Moldova, 1995
The peculiar feature of cybernetic control systems is a feedback interaction with a controlled object. The abstract model of such an interaction may be based on the control and operating automata composition originating in the abstract computer model ...
G. Cejtlin, E. Jushchenko
doaj  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

The role and value of ethical frameworks in software development [PDF]

, 2003
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Software development is notorious for failure, typically defined as over budget, late delivery and/or poor quality of new information systems (IS) on ...
Dodd, Sean
core  

Strategic Learning Under Linguistic and Contextual Constraints: A Theoretical Framework for LLM-Based Multi-Agent Coordination

IEEE Access
This study introduces mathematical frameworks for analyzing strategic coordination in large-language-model-based multi-agent systems operating under context-window limitations and semantic uncertainty.
Sungwook Yoon
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Autonomous fault detection in self-healing systems using Restricted Boltzmann Machines [PDF]

, 2015
Funding for this research was provided by the Scottish Informatics and Computer Science Alliance (SICSA).Autonomously detecting and recovering from faults is one approach for reducing the operational complexity and costs associated with managing ...
Barker, Adam David, Schneider, Christopher, Dobson, Simon Andrew, Adam Barker, Chris Schneider, Simon Dobson   +5 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source