Results 101 to 110 of about 283,444 (362)
La aplicación física de la geometría astral como confirmación de la teoría kantiana del conocimiento
Logos, 2007 The appearance of the non-Euclidean or astral geometries seemed to contradict the philosophy of the Kant´s mathematics. He had considered the possibility of a supreme geometry, but he discarded it due to it was not synthetically related with the ...
Juan Cano de Pablo
doaj
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Indefinite-Metric Quantum Field Theory of General Relativity. XV: Tensorlike Four-Dimensional Commutation Relation [PDF]
, 1982 Noboru Nakanishi
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
2. The Theory of Special Relativity
, 1958 Albert Einstein (1879-1955) published his first work on relativity in 1905, the same year in which he published remarkable papers on Brownian motion and the photoelectric effect.
Bloom, Robert L. +6 more
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A Note on the Axisymmetric Stationary Metric in the General Theory of Relativity [PDF]
, 2019 Tetu Makino
openalex +1 more source
Molecular Oncology, EarlyView.The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat +18 more
wiley +1 more source
Inextendibilty of the Maximal Global Hyperbolic Development in Electrogowdy spacetimes
EPJ Web of Conferences, 2013 The problem of determinism in General Relativity appears even if one assumes that the spacetime is globally hyperbolic, i.e. that it contains a hypersurface that is intersected by any causal curve exactly once.
Nungesser Ernesto
doaj +1 more source
Epistemology of General Relativity [PDF]
For Einstein, simplicity is the main criterion in the theoretical choice when the experiments and observations do not give sufficiently clear indications .
Sfetcu, Nicolae
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