Results 31 to 40 of about 64,636 (261)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Three Decades of Relevance Theory and Relevance-Theoretic Translation of Scientific Register

, 2022
Our paper explores the application of Relevance Theory to the process of translation of scientific register. This register includes the oral and written data pertaining to electrical engineering, computer science and mechanical engineering discourses. The first part of the paper provides some introductory considerations about Relevance Theory.
Miloš D. Đurić, Nada Krnjaić-Cekić
openaire   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Bridges or walls: remarks on translating the concepts of cultural - historical theory

Вестник Московского университета. Серия 14: Психология
Background. The problem of translating scientific articles into other languages affects not only translators but also psychologists, since the accuracy of translation determines the adequacy of understanding and transferring of scientific concepts ...
Elizabeth Tunes , Zoia Ribeiro Prestes
doaj   +1 more source

Systemic Functional Linguistics as Approach to Translation

Zanco Journal of Humanity Sciences, 2021
The significance of linguistics to translation is inevitable, since translation activity involves language, and since linguistics is the scientific study of language (Manfredi, 2008, p. 31).
Yousif Ali Omer , Wrya Izzaddin Ali
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

La présence de la théorie d’Antoine Berman dans les écrits traductologiques polonais vue à travers le prisme de trois revues de traduction choisies

Romanica Wratislaviensia
This study is in line with research projects on the international circulation of knowledge and the role of translation in the transmission of knowledge from one scientific and linguistic community to another.
Kaja Gostkowska
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Modern Thesis Research of Linguoculturological Factors in the Theory and Practice of Translation: Approaches, Gaps, Prospects

Научный диалог, 2021
The thesis research carried out over the past 11 years in line with the culturally oriented concept of translation is considered. The main views on the problems of translation presented in more than 200 thesis in the specialty 10.02.20 for 2009—2020 are ...
N. V. Timko
doaj   +1 more source