Synthesis of Methotrexate loaded Cerium fluoride nanoparticles with pH sensitive extended release coupled with Hyaluronic acid receptor with plausible theranostic capabilities for preclinical safety studies [PDF]
arXiv, 2016 A key challenge in drug delivery systems is the real time monitoring of delivered drug and subsequent response. Recent advancement in nanotechnology has enabled the design and preclinical implementation of novel drug delivery systems (DDS) with theranostic abilities.
arxiv
A Review on Bio-Cyber Interfaces for Intrabody Molecular Communications Systems [PDF]
arXiv, 2021 The recent advancements in bio-engineering and wireless communications systems have motivated researchers to propose novel applications for telemedicine, therapeutics and human health monitoring. For instance, through wireless medical telemetry a healthcare worker can remotely measure biological signals and control certain processes in the organism ...
arxiv
Hyperpolarized Nanodiamond with Long Spin Relaxation Times [PDF]
, 2015 The use of hyperpolarized agents in magnetic resonance (MR), such as 13C-labeled compounds, enables powerful new imaging and detection modalities that stem from a 10,000-fold boost in signal. A major challenge for the future of the hyperpolarizaton technique is the inherently short spin relaxation times, typically < 60 seconds for 13C liquid-state ...
arxiv +1 more source
Liposomes for Cancer Theranostics
Pharmaceutics, 2023 Cancer is one of the most well-studied diseases and there have been significant advancements over the last few decades in understanding its molecular and cellular mechanisms. Although the current treatments (e.g., chemotherapy, radiotherapy, gene therapy and immunotherapy) have provided complete cancer remission for many patients, cancer still remains ...
openaire +3 more sources
COMPARISON OF 68GA-PSMA AND 18F-FDG-PET/CT IN THE ASSESSMENT OF DESMOID TUMORS
Hematology, Transfusion and Cell TherapyIntroduction/Justification: Recently, the tracer Prostate Specific Membrane Antigen (PSMA), which can be labeled with the radioisotopes 68Ga or 18F, has been commercially introduced.
Tobias Luis dos Reis +18 more
doaj
Resting-state functional connectivity-based biomarkers and functional MRI-based neurofeedback for psychiatric disorders: a challenge for developing theranostic biomarkers [PDF]
arXiv, 2017 Psychiatric research has been hampered by an explanatory gap between psychiatric symptoms and their neural underpinnings, which has resulted in poor treatment outcomes. This situation has prompted us to shift from symptom-based diagnosis to data-driven diagnosis, aiming to redefine psychiatric disorders as disorders of neural circuitry.
arxiv
A Statistical Description of Nuclear Reaction Models for Medical Radionuclides: the Paradigmatic Case of $^{47}$Sc Production with Thick Vanadium Targets [PDF]
arXiv, 2020 We have introduced a tool to describe in a simple and efficient way the outcomes of known nuclear reaction codes. It differs from the customary use where typically a specific single model is selected and the remaining disregarded. The use of simple statistical procedures allows to introduce a more general theoretical evaluation with quantitative ...
arxiv
Reprogramming the tumor immune microenvironment using engineered dual-drug loaded Salmonella
Nature CommunicationsSynergistic combinations of immunotherapeutic agents can improve the performance of anti-cancer therapies but may lead to immune-mediated adverse effects. These side-effects can be overcome by using a tumor-specific delivery system.
Dinh-Huy Nguyen +9 more
doaj +1 more source
A novel approach to medical radioisotope production using inverse kinematics: a successful production test of the theranostic radionuclide 67Cu [PDF]
arXiv, 2019 A novel method for the production of important medical radioisotopes has been developed. The approach is based on performing the nuclear reaction in inverse kinematics, namely sending a heavy-ion beam of appropriate energy on a light target (e.g. H, d, He) and collecting the isotope of interest.
arxiv
Theranostics vs theratyping or theranostics plus theratyping?
Journal of Cystic FibrosisTreating all people with Cystic Fibrosis (pwCF) to the level of benefit achieved by highly efficient CFTR modulator therapies (HEMT) remains a significant challenge. Theratyping and theranostics are two distinct approaches to advance CF treatment.
Margarida D. Amaral, Ines Pankonien
openaire +2 more sources