Results 11 to 20 of about 1,011,280 (169)
Confusion of Therapeutic Approaches [PDF]
Deutsches Ärzteblatt international, 2014 Schlitt et al. in their review article focused on cardiotoxic oncological treatments (1). Adequate management of adverse effects of cardiotoxic treatments ensures optimal results of oncological treatment. In the article by Schlitt et al., an algorithm was proposed for monitoring, prevention, and treatment in the context of cardiotoxicity, including the
Ivanyi, Philipp +2 more
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PHARMACOGENETICS APPROACH TO THERAPEUTICS [PDF]
Clinical and Experimental Pharmacology and Physiology, 2006 1. Pharmacogenetics refers to the study of genetically controlled variations in drug response. Functional variants caused by single nucleotide polymorphisms (SNPs) in genes encoding drug-metabolising enzymes, transporters, ion channels and drug receptors have been known to be associated with interindividual and interethnic variation in drug response ...
Seok Hwee, Koo, Edmund Jon Deoon, Lee
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Therapeutic approaches for shankopathies [PDF]
Developmental Neurobiology, 2013 ABSTRACTDespite recent advances in understanding the molecular mechanisms of autism spectrum disorders (ASD), the current treatments for these disorders are mostly focused on behavioral and educational approaches. The considerable clinical and molecular heterogeneity of ASD present a significant challenge to the development of an effective treatment ...
Wang, Xiaoming +4 more
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CASPASE-3 expression and activity in PBMCs associate with SARS-CoV-2 infection and clinical features
Clinical Immunology CommunicationsBackground: Although vaccines and treatments exist, new SARS-CoV-2 variants continue to emerge. An imbalance between apoptosis and autophagy may contribute to COVID-19 pathogenesis, leading to tissue damage and inflammation. Objective: To investigate the
Vanessa Mylenna Florêncio de Carvalho +7 more
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Key Players in HIV-1 Transcriptional Regulation: Targets for a Functional Cure
Viruses, 2020 HIV-1 establishes a life-long infection when proviral DNA integrates into the host genome. The provirus can then either actively transcribe RNA or enter a latent state, without viral production.
Luisa Mori, Susana T. Valente
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Biomedicines, 2021 Interstitial cystitis/bladder pain syndrome (IC/BPS) is a multifactorial, chronic bladder disorder with limited therapeutic options currently available. The present review provides an extensive overview of therapeutic approaches used in in vitro, ex vivo,
Tadeja Kuret +3 more
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Strategizing Drug Therapies in Pulmonary Hypertension for Improved Outcomes
Pharmaceuticals, 2022 Pulmonary hypertension (PH) is characterized by a resting mean pulmonary artery pressure (PAP) of 20 mmHg or more and is a disease of multiple etiologies.
Taylor Beckmann +4 more
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Therapeutic approaches in locked-in syndrome [PDF]
Folia Medica, 2019 Locked-in syndrome (LIS) is a neuropsychological condition, in which patients present with quadriplegia, lower cranial nerve paralysis, and mutism. Diagnosis of LIS is difficult because of the similarities with other related syndromes, but it is of crucial importance to establish precise and early diagnosis in order to make the appropriate decisions ...
Soultana L. Papadopoulou +5 more
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Parasites & VectorsBackground Mosquito saliva plays a key role in arbovirus transmission and pathogenesis. It was shown that saliva contains several molecules that are essential for blood feeding.
Lanjiao Wang +7 more
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Frontiers in PharmacologyOvarian adenocarcinoma is the gynecological malignancy with the worst prognosis and the highest mortality rate. In the first stages of treatment, chemotherapy results effective, but its prolonged use and high doses lead to the appearance of resistance to
Aline Lacroix +5 more
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